SCHEMBL10019804

SCHEMBL10019804

CCCCCc1ccc(C(=O)Oc2ccc3c(c2F)C(F)(F)C(F)(F)c2c-3ccc(CCC)c2F)cc1

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
THRA P10827 7/20 0.41
THRB P10828 7/20 0.41
RARB P10826 7/20 0.41
MEN1 O00255 2/20 0.38
MAPT P10636 2/20 0.38
KMT2A Q03164 2/20 0.38
ALDH1A1 P00352 1/20 0.38
RARA P10276 1/20 0.38
MTOR P42345 1/20 0.38
FAAH O00519 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10019872 0.89 RARB (0.39) THRATHRBRARBMEN1MAPT
SCHEMBL10019794 0.87 THRB (0.35) THRATHRBMEN1KMT2A
SCHEMBL10019873 0.86 RARB (0.40) THRATHRBRARBRARAFAAH
SCHEMBL10020056 0.85 ELANE (0.35) THRATHRBRARBRARA
SCHEMBL10381688 0.84 THRA (0.48) THRATHRBRARBMEN1MAPT
SCHEMBL10382239 0.84 THRA (0.48) THRATHRBRARBMEN1MAPT
SCHEMBL10019362 0.83 ELANE (0.35) THRATHRBRARBRARA
SCHEMBL10019791 0.83 THRB (0.41) THRBMAPTKMT2AALDH1A1SMN1; SMN2
SCHEMBL10019937 0.83 SMPD1 (0.38) THRATHRBRARBALDH1A1
SCHEMBL10019365 0.82 THRB (0.43) THRATHRBRARBMAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2669263-B1 COMPOUND CONTAINING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORP (JP) 2017-11-22 EP disclosed
US-9193908-B2 Compound having dihydrophenanthrene, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-11-24 US disclosed
US-9193908-B2 Compound having dihydrophenanthrene, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-11-24 US disclosed
US-20130240784-A1 COMPOUND HAVING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-09-19 US disclosed
US-20130240784-A1 COMPOUND HAVING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-09-19 US disclosed
WO-2012086437-A1 COMPOUND CONTAINING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY JNC株式会社 (JP) 2012-06-28 WO disclosed