SCHEMBL10019362

SCHEMBL10019362

CCCCCc1ccc(OC(=O)c2ccc3c(c2F)C(F)(F)C(F)(F)c2c-3ccc(CCC)c2F)c(F)c1F

nearest known ligand 0.35

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ELANE P08246 4/20 0.35
CTSL P07711 1/20 0.34
CTSS P25774 1/20 0.34
CTSK P43235 1/20 0.34
PPARA Q07869 3/20 0.33
PPARG P37231 2/20 0.33
RARB P10826 2/20 0.32
THRA P10827 1/20 0.32
THRB P10828 1/20 0.32
RARA P10276 1/20 0.32
RARG P13631 1/20 0.32
TSHR P16473 1/20 0.31
CTSG P08311 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10020056 0.96 ELANE (0.35) ELANECTSLCTSSCTSKPPARA
SCHEMBL10019354 0.88 CTSL (0.37) CTSLCTSSCTSK
SCHEMBL10019674 0.88 PPARA (0.39) PPARAPPARGRARBRARARARG
SCHEMBL10019359 0.87 CTSL (0.35) CTSLCTSSCTSK
SCHEMBL10019365 0.87 THRB (0.43) PPARAPPARGRARBTHRATHRB
SCHEMBL10020067 0.86 CTSL (0.37) CTSLCTSSCTSK
SCHEMBL10019873 0.86 RARB (0.40) PPARAPPARGRARBTHRATHRB
SCHEMBL15257953 0.86 PRSS1 (0.39) ELANERARBRARARARGTSHR
SCHEMBL10019804 0.83 THRA (0.41) RARBTHRATHRBRARA
SCHEMBL10019872 0.83 RARB (0.39) ELANEPPARAPPARGRARBTHRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2669263-B1 COMPOUND CONTAINING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORP (JP) 2017-11-22 EP disclosed
US-9193908-B2 Compound having dihydrophenanthrene, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-11-24 US disclosed
US-9193908-B2 Compound having dihydrophenanthrene, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-11-24 US disclosed
US-20130240784-A1 COMPOUND HAVING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-09-19 US disclosed
US-20130240784-A1 COMPOUND HAVING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-09-19 US disclosed
WO-2012086437-A1 COMPOUND CONTAINING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY JNC株式会社 (JP) 2012-06-28 WO disclosed