SCHEMBL10019935

SCHEMBL10019935

C=CCCc1ccc(COc2ccc3c(c2F)C(F)(F)C(F)(F)c2c-3ccc(OCC)c2F)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.35
TACR2 P21452 1/20 0.34
BCHE P06276 4/20 0.33
L3MBTL1 Q9Y468 2/20 0.32
LMNA P02545 2/20 0.32
GABRA1 P14867 3/20 0.32
GABRB2 P47870 3/20 0.32
KDM4E B2RXH2 3/20 0.31
MAPT P10636 3/20 0.31
ALDH1A1 P00352 2/20 0.31
PKM P14618 1/20 0.31
NTSR1 P30989 1/20 0.31
MRGPRX4 Q96LA9 1/20 0.31
FFAR4 Q5NUL3 2/20 0.31
FFAR1 O14842 1/20 0.31
NPC1 O15118 1/20 0.31
HPGD P15428 1/20 0.31
RAB9A P51151 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
CALM1 P0DP23 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10019960 0.90 GABRA1 (0.35) LMNAGABRA1GABRB2ALDH1A1FFAR4
SCHEMBL10019946 0.89 CTSL (0.35) BCHEL3MBTL1
SCHEMBL10019850 0.89 GABRA1 (0.33) GABRA1GABRB2
SCHEMBL10020113 0.87 PKM (0.36) LMNAGABRA1GABRB2KDM4EMAPT
SCHEMBL10020187 0.87 RXRG (0.36) GAATACR2L3MBTL1LMNAGABRA1
SCHEMBL10020008 0.87 FFAR4 (0.32) BCHEGABRA1GABRB2FFAR4FFAR1
SCHEMBL10019942 0.87 GABRA1 (0.34) GAATACR2BCHEGABRA1GABRB2
SCHEMBL10020125 0.86
SCHEMBL10019987 0.85 GABRA1 (0.32) LMNAGABRA1GABRB2CALM1
SCHEMBL10020015 0.85 PKM (0.33) GABRA1GABRB2PKMFFAR1CALM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2669263-B1 COMPOUND CONTAINING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORP (JP) 2017-11-22 EP disclosed
US-9193908-B2 Compound having dihydrophenanthrene, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-11-24 US disclosed
US-9193908-B2 Compound having dihydrophenanthrene, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-11-24 US disclosed
US-20130240784-A1 COMPOUND HAVING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-09-19 US disclosed
US-20130240784-A1 COMPOUND HAVING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-09-19 US disclosed
WO-2012086437-A1 COMPOUND CONTAINING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY JNC株式会社 (JP) 2012-06-28 WO disclosed