Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 6/20 | 0.76 |
| ▸ | TP53 | P04637 | 3/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | CCR1 | P32246 | 3/20 | 0.64 |
| ▸ | CCR5 | P51681 | 3/20 | 0.64 |
| ▸ | CCR8 | P51685 | 3/20 | 0.64 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.64 |
| ▸ | ALPL | P05186 | 1/20 | 0.64 |
| ▸ | ALPI | P09923 | 1/20 | 0.64 |
| ▸ | ALPG | P10696 | 1/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12575141 | 0.91 | CYP2A6 (0.63) | CYP2A6TP53SMN1; SMN2CCR1CCR5 | |
| SCHEMBL22521564 | 0.88 | CYP2A6 (0.64) | CYP2A6TP53SMN1; SMN2CCR1CCR5 | |
| SCHEMBL14297277 | 0.88 | CYP2A6 (0.63) | CYP2A6TP53SMN1; SMN2CCR1CCR5 | |
| SCHEMBL15459433 | 0.87 | CYP2A6 (0.58) | CYP2A6TP53SMN1; SMN2CCR1CCR5 | |
| SCHEMBL14297281 | 0.87 | CYP2A6 (0.72) | CYP2A6TP53SMN1; SMN2CCR1CCR5 | |
| [2,3'']Bipyridinyl SCHEMBL29389597 | 0.87 | CYP2A6 (1.00) | CYP2A6TP53SMN1; SMN2CCR1CCR5 | |
| [2,3'']Bipyridinyl SCHEMBL29360744 | 0.87 | CYP2A6 (1.00) | CYP2A6TP53SMN1; SMN2CCR1CCR5 | |
| [2,3'']Bipyridinyl SCHEMBL29486847 | 0.87 | CYP2A6 (1.00) | CYP2A6TP53SMN1; SMN2CCR1CCR5 | |
| [2,3'']Bipyridinyl SCHEMBL998601 | 0.87 | CYP2A6 (1.00) | CYP2A6TP53SMN1; SMN2CCR1CCR5 | |
| SCHEMBL3194702 | 0.87 | CYP2A6 (0.74) | CYP2A6TP53SMN1; SMN2HSP90AA1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220202326-A1 | ANALYTE SENSORS WITH METAL-CONTAINING REDOX MEDIATORS AND METHODS OF USING THE SAME | ABBOTT DIABETES CARE INC. (US) | 2022-06-30 | — | — | US | disclosed |
| US-20190144587-A1 | METHOD FOR PRODUCING CONJUGATED DIENE POLYMER | ZEON CORPORATION (JP) | 2019-05-16 | — | — | US | disclosed |
| US-20120052423-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS | CANON KABUSHIKI KAISHA (JP) | 2012-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220202326-A1 | ANALYTE SENSORS WITH METAL-CONTAINING REDOX MEDIATORS AND METHODS OF USING THE SAME | GPX4, LPO, PRDX3 | CYP2A6 1699/4885TP53 1034/4885SMN1; SMN2 4523/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.