Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | APP | P05067 | 6/20 | 0.51 |
| ▸ | METAP1 | P53582 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.49 |
| ▸ | SNCA | P37840 | 2/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5428973 | 0.89 | CYP1A2 (0.67) | MAPTNPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL14089316 | 0.84 | MAPT (0.45) | MAPTNPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL2502424 | 0.83 | TXNRD1 (0.65) | MAPTNPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL14089317 | 0.81 | MAPT (0.48) | MAPTNPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL10621315 | 0.81 | MAPT (0.93) | MAPTNPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL10021997 | 0.81 | MAPT (0.93) | MAPTNPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL3738691 | 0.81 | MAPT (0.93) | MAPTNPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL14089321 | 0.80 | MAPT (0.47) | MAPTNPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL1524517 | 0.79 | ALDH1A1 (0.62) | MAPTNPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL1524516 | 0.79 | ALDH1A1 (0.62) | MAPTNPC1RAB9ASMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119041-B2 | A polymerizable monomer or polymerizable oligomer and at least a two-photon absorption material containing aliphatic ketone compounds with atleast 2-8 double bonds and two aromatic or heteroaromatic rings | FUJIFILM CORPORATION (JP) | 2012-02-21 | — | — | US | disclosed |
| US-8119041-B2 | A polymerizable monomer or polymerizable oligomer and at least a two-photon absorption material containing aliphatic ketone compounds with atleast 2-8 double bonds and two aromatic or heteroaromatic rings | FUJIFILM CORPORATION (JP) | 2012-02-21 | — | — | US | disclosed |