Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.63 |
| ▸ | PNP | P00491 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11688227 | 1.00 | HIF1A (0.63) | HIF1APNPLMNATP53HTT | |
| SCHEMBL29738724 | 1.00 | HIF1A (0.63) | HIF1APNPLMNATP53HTT | |
| SCHEMBL11688219 | 1.00 | HIF1A (0.63) | HIF1APNPLMNATP53HTT | |
| SCHEMBL887520 | 1.00 | HIF1A (0.63) | HIF1APNPLMNATP53HTT | |
| SCHEMBL20129803 | 1.00 | HIF1A (0.63) | HIF1APNPLMNATP53HTT | |
| SCHEMBL17279176 | 0.88 | HIF1A (0.48) | HIF1A | |
| SCHEMBL17231789 | 0.88 | HIF1A (0.48) | HIF1A | |
| SCHEMBL20095278 | 0.88 | HIF1A (0.48) | HIF1A | |
| SCHEMBL3764696 | 0.87 | HIF1A (0.52) | HIF1APNPLMNATP53HTT | |
| SCHEMBL7661650 | 0.85 | HIF1A (0.52) | HIF1APNPLMNATP53HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9528151-B2 | Four-color DNA sequencing by synthesis using cleavable fluorescent nucleotide reversible terminators | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2016-12-27 | — | — | US | disclosed |
| US-20140315191-A1 | FOUR-COLOR DNA SEQUENCING BY SYNTHESIS USING CLEAVABLE FLUORESCENT NUCLEOTIDE REVERSIBLE TERMINATORS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2014-10-23 | — | — | US | disclosed |
| US-20130280700-A1 | FOUR-COLOR DNA SEQUENCING BY SYNTHESIS USING CLEAVABLE FLUORESCENT NUCLEOTIDE REVERSIBLE TERMINATORS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2013-10-24 | — | — | US | disclosed |
| US-8298792-B2 | Four-color DNA sequencing by synthesis using cleavable fluorescent nucleotide reversible terminators | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2012-10-30 | — | — | US | disclosed |
| US-8298792-B2 | Four-color DNA sequencing by synthesis using cleavable fluorescent nucleotide reversible terminators | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2012-10-30 | — | — | US | disclosed |
| US-20120021408-A1 | FOUR-COLOR DNA SEQUENCING BY SYNTHESIS USING CLEAVABLE FLUORESCENT NUCLEOTIDE REVERSIBLE TERMINATORS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2012-01-26 | — | — | US | disclosed |
| US-20120021408-A1 | FOUR-COLOR DNA SEQUENCING BY SYNTHESIS USING CLEAVABLE FLUORESCENT NUCLEOTIDE REVERSIBLE TERMINATORS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2012-01-26 | — | — | US | disclosed |