SCHEMBL20095278

SCHEMBL20095278

CCOCC1OC(n2cnc3c(/N=C/N(C)C)ncnc32)CC1O

nearest known ligand 0.48

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ HIF1A Q16665 1/20 0.48
▸ POLB P06746 1/20 0.45
▸ ENPP1 P22413 2/20 0.44
▸ P2RY1 P47900 1/20 0.44
▸ ADORA3 P0DMS8 1/20 0.42
▸ TYMP P19971 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10022903 0.88 HIF1A (0.63) HIF1A
SCHEMBL20129803 0.88 HIF1A (0.63) HIF1A
SCHEMBL11688227 0.88 HIF1A (0.63) HIF1A
SCHEMBL11688219 0.88 HIF1A (0.63) HIF1A
SCHEMBL887520 0.88 HIF1A (0.63) HIF1A
SCHEMBL29738724 0.88 HIF1A (0.63) HIF1A
SCHEMBL431332 0.87 HIF1A (0.46) HIF1APOLBENPP1P2RY1TYMP
SCHEMBL30821669 0.87 HIF1A (0.46) HIF1APOLBENPP1P2RY1TYMP
SCHEMBL887467 0.87 HIF1A (0.46) HIF1APOLBENPP1P2RY1TYMP
SCHEMBL20129802 0.87 HIF1A (0.46) HIF1APOLBENPP1P2RY1TYMP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3529380-B1 METHODS FOR CHEMICAL LIGATION OF NUCLEIC ACIDS ILLUMINA INC (US) 2022-06-29 — — EP disclosed
WO-2018075785-A9 METHODS FOR CHEMICAL LIGATION OF NUCLEIC ACIDS ILLUMINA, INC. (US) 2018-06-21 — — WO disclosed
WO-2018075785-A1 METHODS FOR CHEMICAL LIGATION OF NUCLEIC ACIDS ILLUMINA, INC. (US) 2018-04-26 — — WO disclosed
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