Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.38 |
| ▸ | ADA | P00813 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19771224 | 0.89 | HIF1A (0.46) | HIF1ASLC29A1ADA | |
| SCHEMBL10022903 | 0.88 | HIF1A (0.63) | HIF1A | |
| SCHEMBL29738724 | 0.88 | HIF1A (0.63) | HIF1A | |
| SCHEMBL887520 | 0.88 | HIF1A (0.63) | HIF1A | |
| SCHEMBL11688219 | 0.88 | HIF1A (0.63) | HIF1A | |
| SCHEMBL20129803 | 0.88 | HIF1A (0.63) | HIF1A | |
| SCHEMBL11688227 | 0.88 | HIF1A (0.63) | HIF1A | |
| SCHEMBL17279176 | 0.86 | HIF1A (0.48) | HIF1ASLC29A1 | |
| SCHEMBL887896 | 0.82 | ALDH1A1 (0.51) | HIF1AADA | |
| SCHEMBL22327401 | 0.79 | HIF1A (0.42) | HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3137479-B1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF MAKING THE SAME | GERON CORP (US) | 2023-08-30 | — | — | EP | disclosed |
| US-11739114-B2 | Oligonucleotide compositions and methods of making the same | GERON CORPORATION (US) | 2023-08-29 | — | — | US | disclosed |
| US-10392418-B2 | Oligonucleotide compositions and methods of making the same | GERON CORPORATION (US) | 2019-08-27 | — | — | US | disclosed |
| US-20180016293-A1 | Oligonucleotide Compositions and Methods of Making the Same | BIOPHARMA CREDIT PLC [COLLATERAL AGENT] (GB) | 2018-01-18 | — | — | US | disclosed |
| US-20180016293-A1 | Oligonucleotide Compositions and Methods of Making the Same | BIOPHARMA CREDIT PLC [COLLATERAL AGENT] (GB) | 2018-01-18 | — | — | US | disclosed |
| US-9796747-B2 | Oligonucleotide compositions and methods of making the same | GERON CORPORATION (US) | 2017-10-24 | — | — | US | disclosed |
| US-9796747-B2 | Oligonucleotide compositions and methods of making the same | GERON CORPORATION (US) | 2017-10-24 | — | — | US | disclosed |
| US-20150337314-A1 | Oligonucleotide Compositions and Methods of Making the Same | BIOPHARMA CREDIT PLC [COLLATERAL AGENT] (GB) | 2015-11-26 | — | — | US | disclosed |
| US-20150337314-A1 | Oligonucleotide Compositions and Methods of Making the Same | BIOPHARMA CREDIT PLC [COLLATERAL AGENT] (GB) | 2015-11-26 | — | — | US | disclosed |
| WO-2015168310-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF MAKING THE SAME | GERON CORPORATION (US) | 2015-11-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150337314-A1 | Oligonucleotide Compositions and Methods of Making the Same | RNGTT, NSUN2, POLN | HIF1A 4016/4885SLC29A1 367/4885ADA 240/4885 |
| US-11739114-B2 | Oligonucleotide compositions and methods of making the same | RNGTT, NSUN2, POLN | HIF1A 4016/4885SLC29A1 367/4885ADA 240/4885 |
| US-10392418-B2 | Oligonucleotide compositions and methods of making the same | RNGTT, NSUN2, POLN | HIF1A 4016/4885SLC29A1 367/4885ADA 240/4885 |
| US-20180016293-A1 | Oligonucleotide Compositions and Methods of Making the Same | RNGTT, NSUN2, POLN | HIF1A 4016/4885SLC29A1 367/4885ADA 240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.