Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 4/20 | 0.46 |
| ▸ | FBP1 | P09467 | 2/20 | 0.46 |
| ▸ | KDM4A | O75164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | PHGDH | O43175 | 1/20 | 0.43 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10023936 | 0.91 | ALDH1A1 (0.55) | MGLLFBP1KDM4AALDH1A1PHGDH | |
| SCHEMBL10954952 | 0.75 | MGLL (0.41) | MGLLFBP1KDM4AALDH1A1PHGDH | |
| SCHEMBL4602642 | 0.71 | — | — | |
| SCHEMBL10822547 | 0.69 | ALDH1A1 (0.44) | MGLLFBP1KDM4AALDH1A1PHGDH | |
| SCHEMBL9529001 | 0.69 | ALDH1A1 (0.50) | MGLLFBP1KDM4AALDH1A1PHGDH | |
| SCHEMBL1535830 | 0.69 | ALDH1A1 (0.50) | MGLLFBP1KDM4AALDH1A1PHGDH | |
| SCHEMBL14340049 | 0.69 | MGLL (0.88) | MGLLFBP1KDM4AALDH1A1PHGDH | |
| SCHEMBL23314068 | 0.67 | ALDH1A1 (0.48) | MGLLFBP1KDM4AALDH1A1PHGDH | |
| SCHEMBL23314066 | 0.67 | ALDH1A1 (0.48) | MGLLFBP1KDM4AALDH1A1PHGDH | |
| SCHEMBL21538410 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119316-B2 | Thiuram tetrasulfide containing photogenerating layer | XEROX CORPORATION (US) | 2012-02-21 | — | — | US | disclosed |
| US-20090246658-A1 | THIURAM TETRASULFIDE CONTAINING PHOTOGENERATING LAYER | XEROX CORPORATION (US) | 2009-10-01 | — | — | US | disclosed |