Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 11/20 | 0.88 |
| ▸ | FBP1 | P09467 | 2/20 | 0.88 |
| ▸ | KDM4A | O75164 | 1/20 | 0.88 |
| ▸ | PHGDH | O43175 | 8/20 | 0.83 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.83 |
| ▸ | ALDH2 | P05091 | 2/20 | 0.83 |
| ▸ | PDK1 | Q15118 | 5/20 | 0.62 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.62 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.62 |
| ▸ | FAAH | O00519 | 2/20 | 0.59 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bis(Pyrrolidinylthiocarbonyl)Disulfide SCHEMBL2237172 | 0.94 | MGLL (1.00) | MGLLFBP1KDM4APHGDHALDH1A1 | |
| SCHEMBL3271164 | 0.91 | MGLL (1.00) | MGLLFBP1KDM4APHGDHALDH1A1 | |
| Bis(Piperidinylthiocarbonyl)Disulfide SCHEMBL139465 | 0.91 | MGLL (1.00) | MGLLFBP1KDM4APHGDHALDH1A1 | |
| SCHEMBL11811976 | 0.87 | MGLL (0.77) | MGLLFBP1KDM4APHGDHALDH1A1 | |
| SCHEMBL1195559 | 0.83 | MGLL (0.83) | MGLLFBP1KDM4APHGDHALDH1A1 | |
| SCHEMBL13668385 | 0.82 | MGLL (0.79) | MGLLFBP1KDM4APHGDHALDH1A1 | |
| SCHEMBL10976857 | 0.80 | MGLL (0.80) | MGLLFBP1KDM4APHGDHALDH1A1 | |
| SCHEMBL22910 | 0.80 | MGLL (0.80) | MGLLFBP1KDM4APHGDHALDH1A1 | |
| SCHEMBL11825600 | 0.78 | MGLL (0.71) | MGLLFBP1KDM4APHGDHALDH1A1 | |
| SCHEMBL10887385 | 0.78 | MGLL (0.76) | MGLLFBP1KDM4APHGDHALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070299043-A1 | Anti-scarring drug combinations and use thereof | HUNTER WILLIAM L | 2007-12-27 | — | — | US | disclosed |
| US-20070208134-A1 | Anti-scarring drug combinations and use thereof | HUNTER WILLIAM L | 2007-09-06 | — | — | US | disclosed |
| US-20070196421-A1 | Soft tissue implants and drug combination compositions, and use thereof | ANGIOTECH INTERNATIONAL AG (CH) | 2007-08-23 | — | — | US | disclosed |
| US-20070198063-A1 | Electrical devices and anti-scarring drug combinations | HUNTER WILLIAM L | 2007-08-23 | — | — | US | disclosed |
| US-20070197957-A1 | Implantable sensors, implantable pumps and anti-scarring drug combinations | HUNTER WILLIAM L | 2007-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070208134-A1 | Anti-scarring drug combinations and use thereof | MMP1, COL2A1, COL1A1 | MGLL 2536/4885FBP1 4624/4885KDM4A 1189/4885 |
| US-20070196421-A1 | Soft tissue implants and drug combination compositions, and use thereof | COL2A1, MMP1, FN1 | MGLL 443/4885FBP1 2687/4885KDM4A 1797/4885 |
| US-20070299043-A1 | Anti-scarring drug combinations and use thereof | MMP1, COL2A1, COL1A1 | MGLL 2536/4885FBP1 4624/4885KDM4A 1189/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.