SCHEMBL10023959

SCHEMBL10023959

CC1COC(C(=O)O)C(C)C1C

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SUCNR1 Q9BXA5 1/20 0.36
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
PPP5C P53041 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11621138 0.93 SUCNR1 (0.38) SUCNR1PPP5C
SCHEMBL31536562 0.83
SCHEMBL9804585 0.83
SCHEMBL31536659 0.83
SCHEMBL18822220 0.77 THRB (0.40) SUCNR1
SCHEMBL11567212 0.77 PPP5C (0.39) SUCNR1KDM4EALDH1A1PPP5C
SCHEMBL12997172 0.76 SUCNR1 (0.35) SUCNR1PPP5C
SCHEMBL15182536 0.76 PPP5C (0.38) SUCNR1KDM4EPPP5C
SCHEMBL18068842 0.74 THRB (0.37) SUCNR1
SCHEMBL13480352 0.74 THRB (0.37) SUCNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9346893-B2 Process for the preparation of highly O-sulfated, epimerized derivatives of K5 polysacchride and intermediates therein GLYCORES 2000 S.R.L. (IT) 2016-05-24 US disclosed
US-20140316129-A1 PROCESS FOR THE PREPARATION OF HIGHLY O-SULFATED, EPIMERIZED DERIVATIVES OF K5 POLYSACCHRIDE AND INTERMEDIATES THEREIN GLYCORES 2000 S.R.L. (IT) 2014-10-23 US disclosed
US-20120253029-A1 PROCESS FOR THE PREPARATION OF HIGHLY O-SULFATED EPIMERIZED DERIVATIVES OF K5 POLYSACCHARIDE AND INTERMEDIATES THEREIN GLYCORES 2000 S.R.L. (IT) 2012-10-04 US disclosed
US-8193166-B2 Epimerized derivatives of K5 polysaccharide with a very high degree of sulfation GLYCORES 2000 S.R.L. (IT) 2012-06-05 US disclosed
US-20110021766-A1 EPIMERIZED DERIVATIVES OF K5 POLYSACCHARIDE WITH A VERY HIGH DEGREE OF SULFATION Glycores 2000 S.r.L (IT) 2011-01-27 US disclosed