Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 2/20 | 0.39 |
| ▸ | RXRB | P28702 | 2/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RXRG | P48443 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.37 |
| ▸ | ICMT | O60725 | 1/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14524942 | 0.86 | RXRA (0.41) | S1PR1RXRARXRBRXRGGRIN1 | |
| SCHEMBL5263743 | 0.86 | PDCD1 (0.48) | S1PR1RXRARXRBRAB9ARXRG | |
| SCHEMBL19111150 | 0.86 | KIF11 (0.43) | S1PR1RXRARXRBRXRGGRIN1 | |
| SCHEMBL7945344 | 0.84 | TNKS2 (0.40) | S1PR1RXRARXRBRXRGGRIN1 | |
| SCHEMBL14524935 | 0.84 | ALOX5 (0.44) | S1PR1RXRARXRBRXRGGRIN1 | |
| SCHEMBL14609645 | 0.84 | S1PR1 (0.38) | S1PR1RXRARXRBRXRGGRIN1 | |
| SCHEMBL14525317 | 0.84 | S1PR1 (0.41) | S1PR1RXRARXRBRAB9AMEN1 | |
| SCHEMBL7330961 | 0.83 | HPGD (0.44) | MCL1RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL21753414 | 0.82 | PRKCI (0.49) | S1PR1RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL95787 | 0.82 | TP53 (0.48) | RAB9AMEN1KMT2ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120232242-A1 | THIAZOLOTHIAZOLE COMPOUND AND THIAZOLOTHIAZOLE POLYMER | FUJI XEROX CO., LTD. (JP) | 2012-09-13 | — | — | US | disclosed |
| US-8207348-B2 | Thiazolothiazole compound and thiazolothiazole polymer | FUJI XEROX CO., LTD. (JP) | 2012-06-26 | — | — | US | disclosed |
| US-20110086999-A1 | THIAZOLOTHIAZOLE COMPOUND AND THIAZOLOTHIAZOLE POLYMER | FUJI XEROX CO., LTD. (JP) | 2011-04-14 | — | — | US | disclosed |
| US-20070149570-A1 | Piperidine derivative and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-06-28 | — | — | US | disclosed |
| WO-2007015588-A1 | PIPERIDINE DERIVATIVE AS TACHYKININ RECEPTOR ANTAGONIST | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070149570-A1 | Piperidine derivative and use thereof | TACR1, OPRL1, TRPV1 | S1PR1 94/4885RXRA 3555/4885RXRB 3372/4885 |
| US-20110086999-A1 | THIAZOLOTHIAZOLE COMPOUND AND THIAZOLOTHIAZOLE POLYMER | ARL1, IRAK1, TYK2 | S1PR1 3848/4885RXRA 2472/4885RXRB 2112/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.