Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1001608 | 0.87 | LMNA (0.36) | ALDH1A1KDM4EUSP2ALOX15HTT | |
| SCHEMBL13912883 | 0.79 | KDM4E (0.46) | ALDH1A1KDM4EUSP2ALOX15HTT | |
| SCHEMBL1001771 | 0.79 | ALDH1A1 (0.40) | ALDH1A1KDM4EUSP2ALOX15TP53 | |
| SCHEMBL1244968 | 0.79 | ALDH1A1 (0.42) | ALDH1A1KDM4EUSP2ALOX15TP53 | |
| SCHEMBL13705970 | 0.76 | KDM4E (0.48) | ALDH1A1KDM4EUSP2ALOX15HTT | |
| SCHEMBL12153683 | 0.75 | KDM4E (0.47) | ALDH1A1KDM4EUSP2ALOX15HTT | |
| SCHEMBL301624 | 0.74 | KDM4E (0.48) | ALDH1A1KDM4EUSP2ALOX15HTT | |
| SCHEMBL301438 | 0.74 | KDM4E (0.48) | ALDH1A1KDM4EUSP2ALOX15HTT | |
| SCHEMBL12153675 | 0.73 | KDM4E (0.46) | ALDH1A1KDM4EUSP2ALOX15HTT | |
| SCHEMBL14514525 | 0.72 | ALDH1A1 (0.45) | ALDH1A1KDM4EUSP2ALOX15HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8470894-B2 | Hydrolysis resistant organomodified trisiloxane ionic surfactants | MOMENTIVE PERFORMANCE MATERIALS (US) | 2013-06-25 | — | — | US | disclosed |
| US-8470894-B2 | Hydrolysis resistant organomodified trisiloxane ionic surfactants | MOMENTIVE PERFORMANCE MATERIALS (US) | 2013-06-25 | — | — | US | disclosed |
| US-8263669-B2 | Hydrolysis resistant organomodified trisiloxane ionic surfactants | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2012-09-11 | — | — | US | disclosed |
| US-20120142535-A1 | HYDROLYSIS RESISTANT ORGANOMODIFIED TRISILOXANE IONIC SURFACTANTS | MOMENTIVE PERFORMANCE MATERIALS INC. | 2012-06-07 | — | — | US | disclosed |
| US-20110028569-A1 | MIXTURES OF HYDROLYSIS RESISTANT ORGANOMODIFIED TRISILOXANE IONIC SURFACTANTS | MOMENTIVE PERFORMANCE MATERIALS INC. | 2011-02-03 | — | — | US | disclosed |
| US-20110021644-A1 | HYDROLYSIS RESISTANT ORGANOMODIFIED TRISILOXANE IONIC SURFACTANTS | MOMENTIVE PERFORMANCE MATERIALS INC. | 2011-01-27 | — | — | US | disclosed |
| US-20090173912-A1 | MIXTURES OF HYDROLYSIS RESISTANT ORGANOMODIFIED TRISILOXANE IONIC SURFACTANTS | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2009-07-09 | — | — | US | disclosed |
| US-20090176893-A1 | HYDROLYSIS RESISTANT ORGANOMODIFIED TRISILOXANE IONIC SURFACTANTS | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2009-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110028569-A1 | MIXTURES OF HYDROLYSIS RESISTANT ORGANOMODIFIED TRISILOXANE IONIC SURFACTANTS | CHRM1, CHRM2, CD209 | ALDH1A1 4311/4885KDM4E 2604/4885USP2 754/4885 |
| US-20090176893-A1 | HYDROLYSIS RESISTANT ORGANOMODIFIED TRISILOXANE IONIC SURFACTANTS | CHRM2, CHRM1, MSR1 | ALDH1A1 3424/4885KDM4E 1219/4885USP2 178/4885 |
| US-20120142535-A1 | HYDROLYSIS RESISTANT ORGANOMODIFIED TRISILOXANE IONIC SURFACTANTS | CHRM2, CHRM1, MSR1 | ALDH1A1 3518/4885KDM4E 1089/4885USP2 176/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.