Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1001771 | 0.88 | ALDH1A1 (0.40) | ALDH1A1KDM4EUSP2ALOX15TP53 | |
| SCHEMBL1244429 | 0.87 | ALDH1A1 (0.40) | ALDH1A1KDM4EUSP2ALOX15KMT2A | |
| SCHEMBL12621150 | 0.86 | ALDH1A1 (0.45) | ALDH1A1KDM4EUSP2ALOX15KMT2A | |
| SCHEMBL1245084 | 0.85 | USP2 (0.46) | ALDH1A1KDM4EUSP2ALOX15ADRB2 | |
| SCHEMBL1244331 | 0.84 | SMN1; SMN2 (0.48) | ALDH1A1KDM4EUSP2ALOX15KMT2A | |
| SCHEMBL10024562 | 0.79 | ALDH1A1 (0.39) | ALDH1A1KDM4EUSP2ALOX15TP53 | |
| SCHEMBL12926860 | 0.78 | KDM4E (0.46) | ALDH1A1KDM4EUSP2ALOX15KMT2A | |
| SCHEMBL3879051 | 0.77 | — | — | |
| SCHEMBL1245261 | 0.75 | HTT (0.53) | ALDH1A1USP2KMT2AMEN1HTT | |
| SCHEMBL301438 | 0.75 | KDM4E (0.48) | ALDH1A1KDM4EUSP2ALOX15KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2124545-B1 | HYDROLYSIS RESISTANT ORGANOMODIFIED SILYLATED IONIC SURFACTANTS | MOMENTIVE PERFORMANCE MAT INC (US) | 2015-12-02 | — | — | EP | disclosed |
| EP-2124545-B1 | HYDROLYSIS RESISTANT ORGANOMODIFIED SILYLATED IONIC SURFACTANTS | MOMENTIVE PERFORMANCE MAT INC (US) | 2015-12-02 | — | — | EP | disclosed |
| US-8569385-B2 | Hydrolysis resistant organomodified silylated ionic surfactants | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2013-10-29 | — | — | US | disclosed |
| US-8569385-B2 | Hydrolysis resistant organomodified silylated ionic surfactants | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2013-10-29 | — | — | US | disclosed |
| US-8569385-B2 | Hydrolysis resistant organomodified silylated ionic surfactants | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2013-10-29 | — | — | US | disclosed |
| US-20110105428-A1 | HYDROLYSIS RESISTANT ORGANOMODIFIED SILYLATED IONIC SURFACTANTS | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2011-05-05 | — | — | US | disclosed |
| US-20110105428-A1 | HYDROLYSIS RESISTANT ORGANOMODIFIED SILYLATED IONIC SURFACTANTS | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2011-05-05 | — | — | US | disclosed |
| US-7879916-B2 | Anionic, cationic or zwitterionic disilane surfactants; stable over a wide pH range; for controlling wetting, spreading, foaming, and detergency on applied surfaces; aqueous solutions improve delivery of active ingredients | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2011-02-01 | — | — | US | disclosed |
| US-7879916-B2 | Anionic, cationic or zwitterionic disilane surfactants; stable over a wide pH range; for controlling wetting, spreading, foaming, and detergency on applied surfaces; aqueous solutions improve delivery of active ingredients | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2011-02-01 | — | — | US | disclosed |
| US-20080167389-A1 | Hydrolysis resistant organomodified silylated ionic surfactants | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2008-07-10 | — | — | US | disclosed |
| US-20080167389-A1 | Hydrolysis resistant organomodified silylated ionic surfactants | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2008-07-10 | — | — | US | disclosed |
| US-20080167269-A1 | HYDROLYSIS RESISTANT ORGANOMODIFIED SILYLATED IONIC SURFACTANTS | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2008-07-10 | — | — | US | disclosed |
| US-20080167269-A1 | HYDROLYSIS RESISTANT ORGANOMODIFIED SILYLATED IONIC SURFACTANTS | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2008-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110105428-A1 | HYDROLYSIS RESISTANT ORGANOMODIFIED SILYLATED IONIC SURFACTANTS | MLNR, SSTR3, FOXM1 | ALDH1A1 2282/4885KDM4E 1802/4885USP2 664/4885 |
| US-20080167389-A1 | Hydrolysis resistant organomodified silylated ionic surfactants | MLNR, SSTR3, FOXM1 | ALDH1A1 2282/4885KDM4E 1802/4885USP2 664/4885 |
| US-20080167269-A1 | HYDROLYSIS RESISTANT ORGANOMODIFIED SILYLATED IONIC SURFACTANTS | MLNR, SSTR3, FOXM1 | ALDH1A1 2282/4885KDM4E 1802/4885USP2 664/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.