SCHEMBL10025575

SCHEMBL10025575

O=Nc1c2ccccc2c(N=O)c2ccccc12

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.64
MAPK10 P53779 9/20 0.44
MAPK8 P45983 8/20 0.44
MAPK9 P45984 8/20 0.44
CSNK1D P48730 1/20 0.44
PIK3CG P48736 1/20 0.44
MKNK2 Q9HBH9 1/20 0.44
GRIN2D O15399 1/20 0.43
GRIN3B O60391 1/20 0.43
GRIN1 Q05586 1/20 0.43
GRIN2A Q12879 1/20 0.43
GRIN2B Q13224 1/20 0.43
GRIN2C Q14957 1/20 0.43
GRIN3A Q8TCU5 1/20 0.43
RAB9A P51151 4/20 0.41
MAPK1 P28482 3/20 0.41
MAPT P10636 3/20 0.41
KMT2A Q03164 3/20 0.41
MEN1 O00255 2/20 0.41
ALDH1A1 P00352 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10025574 0.81 ALDH1A1 (0.46) HSP90AA1KMT2AMEN1ALDH1A1LMNA
SCHEMBL2599158 0.79 HSP90AA1 (1.00) HSP90AA1MAPK10MAPK8MAPK9CSNK1D
SCHEMBL7202159 0.77 HSP90AA1 (0.79) HSP90AA1MAPK10MAPK8MAPK9CSNK1D
SCHEMBL7072802 0.76 ALDH1A1 (0.56) HSP90AA1MAPK10MAPK8MAPK9CSNK1D
SCHEMBL9296347 0.75 HSP90AA1 (0.57) HSP90AA1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL8179362 0.72 HSP90AA1 (0.70) HSP90AA1MAPK10MAPK8MAPK9GRIN2D
SCHEMBL1275295 0.71 ALDH1A1 (0.47) HSP90AA1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL23912940 0.71 HSP90AA1 (0.62) HSP90AA1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL6407030 0.71 HSP90AA1 (0.42) HSP90AA1MAPK10MAPK8MAPK9CSNK1D
SCHEMBL1275863 0.70 HSP90AA1 (0.47) HSP90AA1GRIN2DGRIN3BGRIN1GRIN2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11767452-B2 Curable composition, especially as crystallizing rubber to substrate bonding primer HENKEL AG & CO. KGAA (DE) 2023-09-26 US disclosed
US-11767452-B2 Curable composition, especially as crystallizing rubber to substrate bonding primer HENKEL AG & CO. KGAA (DE) 2023-09-26 US disclosed
EP-3369770-B1 CURABLE COMPOSITION, ESPECIALLY AS CRYSTALLIZING RUBBER TO SUBSTRATE BONDING PRIMER HENKEL AG & CO KGAA (DE) 2021-12-22 EP disclosed
EP-2895546-B1 IMPROVED BONDING COMPOSITION COMPRISING A SULFUR IMPREGNATED PARTICULATE SOLID Henkel IP & Holding GmbH (DE) 2020-06-10 EP disclosed
EP-2895544-B1 IMPROVED BONDING COMPOSITIONS Henkel IP & Holding GmbH (DE) 2018-07-11 EP disclosed
US-20180163101-A1 CURABLE COMPOSITION, ESPECIALLY FOR RUBBER TO SUBSTRATE BONDING HENKEL AG & CO. KGAA (DE) 2018-06-14 US disclosed
US-20180163101-A1 CURABLE COMPOSITION, ESPECIALLY FOR RUBBER TO SUBSTRATE BONDING HENKEL AG & CO. KGAA (DE) 2018-06-14 US disclosed
US-9909039-B2 Bonding compositions Henkel IP Holding GmbH (DE) 2018-03-06 US disclosed
US-9909039-B2 Bonding compositions Henkel IP Holding GmbH (DE) 2018-03-06 US disclosed
US-9790348-B2 Bonding composition comprising a sulfur impregnated particulate solid HENKEL AG & CO. KGAA (DE) 2017-10-17 US disclosed
US-20120202091-A1 PHOSPHONATE BONDING COMPOSITIONS LOCTITE (R&D) LIMITED (IE) 2012-08-09 US disclosed
US-20120202091-A1 PHOSPHONATE BONDING COMPOSITIONS LOCTITE (R&D) LIMITED (IE) 2012-08-09 US disclosed
US-20120193029-A1 COMPOSITIONS FOR POLYMER BONDING LOCTITE (R&D) LIMITED (IE) 2012-08-02 US disclosed
US-20120193029-A1 COMPOSITIONS FOR POLYMER BONDING LOCTITE (R&D) LIMITED (IE) 2012-08-02 US disclosed
US-20120164904-A1 BONDING COMPOSITIONS LOCTITE (R&D) LIMITED (IE) 2012-06-28 US disclosed
US-20120164904-A1 BONDING COMPOSITIONS LOCTITE (R&D) LIMITED (IE) 2012-06-28 US disclosed
WO-2011032998-A1 PHOSPHONATE BONDING COMPOSITIONS LOCTITE (R&D) LIMITED (IE) 2011-03-24 WO disclosed
WO-2011029752-A1 COMPOSITIONS FOR POLYMER BONDING LOCTITE (R & D) LIMITED (IE) 2011-03-17 WO disclosed
WO-2011029751-A1 BONDING COMPOSITIONS LOCTITE (R & D) LIMITED (IE) 2011-03-17 WO disclosed
WO-2009118255-A1 POLYMER TO METAL BONDING AND COMPOUNDS AND COMPOSITIONS USEFUL THEREFOR LOCTITE (R & D) LIMITED (IE) 2009-10-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120164904-A1 BONDING COMPOSITIONS AOX1, NOXO1, RIOX2 HSP90AA1 2383/4885MAPK10 1921/4885MAPK8 3098/4885
US-20120202091-A1 PHOSPHONATE BONDING COMPOSITIONS NOXO1, DDO, PTK2 HSP90AA1 2922/4885MAPK10 329/4885MAPK8 1546/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.