Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 3/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 5/20 | 0.33 |
| ▸ | HTR2C | P28335 | 5/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19705565 | 0.81 | HTR2C (0.33) | HTR2AHTR2CADRB2HTR2B | |
| SCHEMBL14962429 | 0.81 | — | — | |
| SCHEMBL27800792 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL14956310 | 0.80 | ADRB2 (0.31) | ADRB2 | |
| SCHEMBL10025631 | 0.78 | CTSS (0.30) | — | |
| SCHEMBL14956735 | 0.78 | LIPG (0.30) | LIPG | |
| SCHEMBL28783649 | 0.77 | ADRB2 (0.39) | LIPGHTR2AHTR2CADRB2HTR2B | |
| SCHEMBL14955967 | 0.76 | HTR2A (0.33) | LIPGHTR2AHTR2C | |
| SCHEMBL10025712 | 0.75 | SCN9A (0.33) | HTR2AHTR2C | |
| SCHEMBL27779676 | 0.75 | HRH4 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012019427-A1 | PHTHALAZINONE KETONE DERIVATIVE, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL USE THEREOF | 上海恒瑞医药有限公司 (CN) | 2012-02-16 | — | — | WO | disclosed |