Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.70 |
| ▸ | MAOA | P21397 | 2/20 | 0.65 |
| ▸ | MAOB | P27338 | 2/20 | 0.65 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | GRM5 | P41594 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10025789 | 0.89 | MAOA (0.70) | ALDH1A1MAOAMAOBNPC1RAB9A | |
| SCHEMBL10025785 | 0.79 | MAOA (1.00) | ALDH1A1MAOAMAOBNPC1RAB9A | |
| SCHEMBL10025796 | 0.79 | ALDH1A1 (0.65) | ALDH1A1MAOBNPC1RAB9AGRM5 | |
| SCHEMBL10025786 | 0.78 | ALDH1A1 (0.62) | ALDH1A1MAOAMAOBNPC1RAB9A | |
| SCHEMBL5035975 | 0.75 | POLB (0.52) | ALDH1A1 | |
| SCHEMBL9957176 | 0.73 | MAOA (0.80) | ALDH1A1MAOAMAOBNPC1RAB9A | |
| SCHEMBL4420076 | 0.73 | CYP2C19 (0.55) | ALDH1A1MAOAMAOBGRM5SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4420041 | 0.72 | CYP2C19 (0.54) | ALDH1A1MAOAMAOBGRM5SMN1; SMN2 | |
| SCHEMBL10025798 | 0.71 | ALDH1A1 (1.00) | ALDH1A1MAOAMAOBNPC1RAB9A | |
| SCHEMBL4419954 | 0.71 | CYP2C19 (0.52) | ALDH1A1MAOAMAOBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8481459-B2 | Chemical inhibitors of ethylene biosynthesis | ACADEMIA SINICA (TW) | 2013-07-09 | — | — | US | disclosed |
| US-20120023625-A1 | CHEMICAL INHIBITORS OF ETHYLENE BIOSYNTHESIS | ACADEMIA SINICA (TW) | 2012-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120023625-A1 | CHEMICAL INHIBITORS OF ETHYLENE BIOSYNTHESIS | COASY, ACACB, FDPS | ALDH1A1 535/4885MAOA 1237/4885MAOB 1056/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.