Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | HRH1 | P35367 | 3/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD5 | P21918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10025817 | 0.85 | MEN1 (0.35) | KMT2AMEN1DRD1 | |
| SCHEMBL10025837 | 0.81 | KMT2A (0.49) | KMT2AALDH1A1HRH1KCNH2HTR2B | |
| SCHEMBL10025818 | 0.80 | MAOA (0.35) | KMT2AALDH1A1HRH1KCNH2HTR2B | |
| SCHEMBL19504385 | 0.74 | MAOA (0.42) | KMT2AALDH1A1HRH1KCNH2HTR2B | |
| SCHEMBL28135189 | 0.69 | SRD5A1 (0.35) | MAOAMAOB | |
| SCHEMBL10025839 | 0.65 | MAOA (0.39) | KMT2AALDH1A1LMNACYP1A2KDM4E | |
| SCHEMBL19888558 | 0.64 | KDM4E (0.34) | TSHRKDM4EMAPK1 | |
| SCHEMBL10025838 | 0.64 | ITGB2 (0.46) | KMT2AMEN1DRD1LMNATSHR | |
| SCHEMBL10025821 | 0.63 | ALDH1A1 (0.34) | KMT2AALDH1A1HRH1KCNH2HTR2B | |
| SCHEMBL132696 | 0.62 | MAOB (0.60) | KMT2AALDH1A1HRH1KCNH2HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1859005-B1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2016-04-27 | — | — | EP | disclosed |
| US-8124249-B2 | Derivatives of fused aromatic systems; stability; sublimation stability; easy to purify due to better solubilty; easy reproducibility because do not form isomers | MERCK PATENT GMBH (DE) | 2012-02-28 | — | — | US | disclosed |
| US-8124249-B2 | Derivatives of fused aromatic systems; stability; sublimation stability; easy to purify due to better solubilty; easy reproducibility because do not form isomers | MERCK PATENT GMBH (DE) | 2012-02-28 | — | — | US | disclosed |
| US-20080171225-A1 | Novel Materials For Organic Electroluminescent Devices | MERCK PATENT GMBH (DE) | 2008-07-17 | — | — | US | disclosed |
| US-20080171225-A1 | Novel Materials For Organic Electroluminescent Devices | MERCK PATENT GMBH (DE) | 2008-07-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080171225-A1 | Novel Materials For Organic Electroluminescent Devices | OR10J3, EML4, TYR | KMT2A 2174/4885ALDH1A1 1325/4885HRH1 3519/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.