Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 8/20 | 0.61 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.58 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.58 |
| ▸ | PDE2A | O00408 | 3/20 | 0.58 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.58 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA4 | P22748 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.53 |
| ▸ | PNP | P00491 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | NT5E | P21589 | 3/20 | 0.51 |
| ▸ | CD99 | P14209 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10026379 | 1.00 | ADORA3 (0.61) | ADORA3ADORA2AADORA1PDE2APDE4D | |
| SCHEMBL10026381 | 0.91 | ADORA3 (0.59) | ADORA3ADORA2AADORA1PDE2APDE4D | |
| SCHEMBL12139441 | 0.90 | PDE2A (0.67) | ADORA3ADORA2AADORA1PDE2APDE4D | |
| SCHEMBL10026402 | 0.90 | PDE2A (0.67) | ADORA3ADORA2AADORA1PDE2APDE4D | |
| SCHEMBL10026378 | 0.90 | PDE2A (0.67) | ADORA3ADORA2AADORA1PDE2APDE4D | |
| SCHEMBL12139442 | 0.90 | PDE2A (0.67) | ADORA3ADORA2AADORA1PDE2APDE4D | |
| SCHEMBL13046060 | 0.88 | HINT1 (0.53) | ADORA3ADORA2AADORA1ADORA2BNT5E | |
| SCHEMBL13084342 | 0.87 | LMNA (0.47) | ADORA3ADORA2AADORA1PDE2APDE4D | |
| SCHEMBL13046064 | 0.87 | DNMT1 (0.49) | ADORA3ADORA2AADORA1ADORA2BLMNA | |
| SCHEMBL13046058 | 0.86 | NT5E (0.61) | ADORA3ADORA2AADORA1ADORA2BLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8648188-B2 | Preparation of 2-chloro-9-(2′-deoxy-2′-fluoro-β-D-arabinofuranosyl)-adenine | SCINOPHARM TAIWAN, LTD. (TW) | 2014-02-11 | — | — | US | disclosed |
| US-20120010397-A1 | Preparation of 2-chloro-9-(2'-deoxy-2'-fluoro-Beta-D-arabinofuranosyl)-adenine | SCINOPHARM TAIWAN LTD. | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010397-A1 | Preparation of 2-chloro-9-(2'-deoxy-2'-fluoro-Beta-D-arabinofuranosyl)-adenine | HPRT1, TYMP, MTAP | ADORA3 71/4885ADORA2A 55/4885ADORA1 60/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.