SCHEMBL10027331

SCHEMBL10027331

C=C(C)C(=O)OC(C)(C)c1ccc(C(C)(C)OC(=O)C(=C)C)cc1

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.39
KMT2A Q03164 2/20 0.37
ATM Q13315 2/20 0.37
ELANE P08246 1/20 0.36
ALOX15 P16050 1/20 0.34
CYP17A1 P05093 1/20 0.34
CYP19A1 P11511 1/20 0.34
TDP1 Q9NUW8 3/20 0.33
MAPT P10636 1/20 0.33
TSHR P16473 1/20 0.32
MAPK1 P28482 1/20 0.32
POLB P06746 1/20 0.32
APEX1 P27695 1/20 0.32
HTT P42858 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HDAC1 Q13547 1/20 0.31
CYP2C19 P33261 1/20 0.31
HIF1A Q16665 1/20 0.31
SRD5A2 P31213 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16858289 0.94 HDAC1 (0.40) ALDH1A1KMT2AALOX15TDP1MAPT
SCHEMBL26059969 0.93 ESR1 (0.42) ALDH1A1ELANETSHR
SCHEMBL14827345 0.93 TSHR (0.39) ALDH1A1KMT2AATMELANETDP1
SCHEMBL14827400 0.91 CES2 (0.41) ALDH1A1MAPTHDAC1CYP2C19SRD5A2
SCHEMBL14827323 0.91 SMN1; SMN2 (0.40) ALDH1A1KMT2AATMMAPTMAPK1
SCHEMBL24811772 0.91 ALDH1A1 (0.33) ALDH1A1KMT2AATMELANECYP17A1
SCHEMBL3393201 0.90 ALDH1A1 (0.48) ALDH1A1KMT2AATMELANEALOX15
SCHEMBL24667219 0.89 MAPT (0.50) ALDH1A1KMT2AATMELANEALOX15
Ethane SCHEMBL28621749 0.89 ALDH1A1 (0.47) ALDH1A1KMT2AATMELANEALOX15
SCHEMBL16858286 0.88 CYP2C9 (0.43) ALDH1A1KMT2AELANEALOX15MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8193286-B2 Acrylic star polymer NIPPON SODA CO., LTD. (JP) 2012-06-05 US disclosed
US-8193286-B2 Acrylic star polymer NIPPON SODA CO., LTD. (JP) 2012-06-05 US disclosed
US-8067515-B2 Method of producing an acrylic acid-based polymer NIPPON SODA CO., LTD. (JP) 2011-11-29 US disclosed
US-8067515-B2 Method of producing an acrylic acid-based polymer NIPPON SODA CO., LTD. (JP) 2011-11-29 US disclosed
US-20110098413-A1 Acrylic star polymer NIPPON SODA CO., LTD (JP) 2011-04-28 US disclosed
US-20110098413-A1 Acrylic star polymer NIPPON SODA CO., LTD (JP) 2011-04-28 US disclosed
US-20110046333-A1 ACRYLIC ACID-BASED POLYMER AND METHOD OF PRODUCING THE SAME NIPPON SODA CO., LTD. (JP) 2011-02-24 US disclosed
US-20110046333-A1 ACRYLIC ACID-BASED POLYMER AND METHOD OF PRODUCING THE SAME NIPPON SODA CO., LTD. (JP) 2011-02-24 US disclosed
US-7847045-B2 Acrylic acid-based polymer and method of producing the same NIPPON SODA CO., LTD. (JP) 2010-12-07 US disclosed
US-7847045-B2 Acrylic acid-based polymer and method of producing the same NIPPON SODA CO., LTD. (JP) 2010-12-07 US disclosed
US-20090209726-A1 ACRYLIC STAR POLYMER NIPPON SODA CO., LTD. (JP) 2009-08-20 US disclosed
US-20090209726-A1 ACRYLIC STAR POLYMER NIPPON SODA CO., LTD. (JP) 2009-08-20 US disclosed
US-20090111961-A1 Acrylic Acid-Based Polymer and Method of Producing the Same NIPPON SODA CO., LTD. (JP) 2009-04-30 US disclosed
US-20090111961-A1 Acrylic Acid-Based Polymer and Method of Producing the Same NIPPON SODA CO., LTD. (JP) 2009-04-30 US disclosed
US-7494759-B2 Positive resist compositions and process for the formation of resist patterns with the same TOKYO OHKA KOGYO CO., LTD. (JP) 2009-02-24 US disclosed
US-7494759-B2 Positive resist compositions and process for the formation of resist patterns with the same TOKYO OHKA KOGYO CO., LTD. (JP) 2009-02-24 US disclosed
US-20070224538-A1 Positive Resist Compositions and Process for the Formation of Resist Patterns With the Same TOKYO OHKA KOGYO CO., LTD. (JP) 2007-09-27 US disclosed
US-20070224538-A1 Positive Resist Compositions and Process for the Formation of Resist Patterns With the Same TOKYO OHKA KOGYO CO., LTD. (JP) 2007-09-27 US disclosed