Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 1/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.36 |
| ▸ | PRKCG | P05129 | 1/20 | 0.36 |
| ▸ | PRKCB | P05771 | 1/20 | 0.36 |
| ▸ | PRKCA | P17252 | 1/20 | 0.36 |
| ▸ | PRKCH | P24723 | 1/20 | 0.36 |
| ▸ | PRKCI | P41743 | 1/20 | 0.36 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.36 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.36 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.36 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.36 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.36 |
| ▸ | GJB2 | P29033 | 2/20 | 0.35 |
| ▸ | SYNJ2 | O15056 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | STAT3 | P40763 | 7/20 | 0.34 |
| ▸ | GJA1 | P17302 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10027708 | 0.96 | TLR4 (0.41) | TLR4PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL15829725 | 0.90 | TLR4 (0.39) | TLR4PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL19268447 | 0.90 | TLR4 (0.39) | TLR4PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL15829726 | 0.86 | TLR4 (0.41) | TLR4PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL19268443 | 0.86 | TLR4 (0.41) | TLR4PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL19268452 | 0.86 | TLR4 (0.41) | TLR4PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL10027704 | 0.85 | — | — | |
| SCHEMBL10027707 | 0.82 | — | — | |
| SCHEMBL10027706 | 0.81 | PYGB (0.30) | — | |
| SCHEMBL15481358 | 0.80 | TLR4 (0.39) | TLR4PRKD3PRKCGPRKCBPRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9206213-B2 | Methods for pathogen detection and disease treatment | BANGOR UNIVERSITY (GB) | 2015-12-08 | — | — | US | disclosed |
| US-20140178434-A1 | METHOD AND COMPOSITIONS | BANGOR UNIVERSITY (GB) | 2014-06-26 | — | — | US | disclosed |
| US-20120045478-A1 | METHOD AND COMPOSITIONS | BANGOR UNIVERSITY (GB) | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120045478-A1 | METHOD AND COMPOSITIONS | CYP8B1, CYP21A2, HSD17B7 | TLR4 3372/4885PRKD3 2937/4885PRKCG 2487/4885 |
| US-20140178434-A1 | METHOD AND COMPOSITIONS | CYP8B1, CYP17A1, HSD3B1 | TLR4 2957/4885PRKD3 2683/4885PRKCG 3012/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.