SCHEMBL10028033

SCHEMBL10028033

CCOC(=O)C(Cl)(C(=O)OCC)C1CCCC1

nearest known ligand 0.38

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.38
THRB P10828 2/20 0.37
ATM Q13315 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
KMT2A Q03164 2/20 0.36
CYP2D6 P10635 1/20 0.36
NPSR1 Q6W5P4 1/20 0.35
PKM P14618 2/20 0.34
KDM4E B2RXH2 1/20 0.34
MEN1 O00255 1/20 0.34
MAPT P10636 2/20 0.34
FKBP1A P62942 2/20 0.34
CYP4F2 P78329 2/20 0.33
CYP4A11 Q02928 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28867351 0.80 ALDH1A1 (0.40) ALDH1A1THRBATML3MBTL1KMT2A
SCHEMBL23718849 0.79 CYP4F2 (0.33) ALDH1A1THRBKMT2APKMKDM4E
SCHEMBL11467470 0.78 ALDH1A1 (0.39) ALDH1A1THRBATML3MBTL1KMT2A
SCHEMBL7783891 0.78 ALDH1A1 (0.42) ALDH1A1THRBATML3MBTL1KMT2A
SCHEMBL10028034 0.78 ALDH1A1 (0.39) ALDH1A1THRBATML3MBTL1KMT2A
SCHEMBL7608083 0.78 KMT2A (0.41) ALDH1A1THRBATML3MBTL1KMT2A
SCHEMBL28221725 0.78 PKM (0.40) ALDH1A1THRBATML3MBTL1KMT2A
SCHEMBL17420411 0.77 ALDH1A1 (0.39) ALDH1A1THRBATML3MBTL1KMT2A
SCHEMBL11477919 0.77 ALDH1A1 (0.38) ALDH1A1THRBATML3MBTL1KMT2A
SCHEMBL9931238 0.77 ALDH1A1 (0.39) ALDH1A1THRBATML3MBTL1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130150234-A1 Catalyst Composition with Halo-Malonate Internal Electron Donor and Polymer From Same DOW GLOBAL TECHNOLOGIES LLC (US) 2013-06-13 US disclosed
US-20130150234-A1 Catalyst Composition with Halo-Malonate Internal Electron Donor and Polymer From Same DOW GLOBAL TECHNOLOGIES LLC (US) 2013-06-13 US disclosed
US-8383540-B2 Catalyst composition with halo-malonate internal electron donor and polymer from same DOW GLOBAL TECHNOLOGIES LLC (US) 2013-02-26 US disclosed
US-8383540-B2 Catalyst composition with halo-malonate internal electron donor and polymer from same DOW GLOBAL TECHNOLOGIES LLC (US) 2013-02-26 US disclosed
US-20120157296-A1 Catalyst Composition with Halo-Malonate Internal Electron Donor and Polymer From Same W. R. GRACE & CO.-CONN. 2012-06-21 US disclosed
US-20120157296-A1 Catalyst Composition with Halo-Malonate Internal Electron Donor and Polymer From Same W. R. GRACE & CO.-CONN. 2012-06-21 US disclosed