Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 6/20 | 0.50 |
| ▸ | PRNP | P04156 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | CDC25A | P30304 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TYMS | P04818 | 1/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | WDR5 | P61964 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10028077 | 0.84 | AKR1C3 (0.43) | AKR1C3ALDH1A1HSD17B10KMT2AATM | |
| SCHEMBL10028249 | 0.77 | ELANE (0.33) | CDC25BKMT2A | |
| SCHEMBL15293703 | 0.74 | CDC25B (0.67) | CDC25BPRNPAKR1C3ALDH1A1ALOX15 | |
| SCHEMBL31144076 | 0.74 | CDC25B (0.67) | CDC25BPRNPAKR1C3ALDH1A1ALOX15 | |
| SCHEMBL11402284 | 0.73 | ALDH1A1 (0.82) | CDC25BPRNPAKR1C3ALDH1A1ALOX15 | |
| SCHEMBL29977835 | 0.73 | ALDH1A1 (0.82) | CDC25BPRNPAKR1C3ALDH1A1ALOX15 | |
| SCHEMBL809436 | 0.73 | ALDH1A1 (0.82) | CDC25BPRNPAKR1C3ALDH1A1ALOX15 | |
| SCHEMBL19384682 | 0.73 | TYMS (0.77) | CDC25BPRNPAKR1C3ALDH1A1ALOX15 | |
| SCHEMBL87587 | 0.69 | TTR (0.47) | ALDH1A1HSD17B10CYP3A4KMT2ATYMS | |
| SCHEMBL21115371 | 0.68 | TYMS (0.49) | ALDH1A1TYMSLMNAWDR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2046915-B1 | NEW MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2015-12-02 | — | — | EP | disclosed |
| US-8114531-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2012-02-14 | — | — | US | disclosed |
| US-8114531-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2012-02-14 | — | — | US | disclosed |
| US-20100013381-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2010-01-21 | — | — | US | disclosed |
| US-20100013381-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2010-01-21 | — | — | US | disclosed |
| WO-2008011964-A1 | NEW MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2008-01-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100013381-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | L1CAM, SOD1, SLC40A1 | CDC25B 3725/4885PRNP 1944/4885AKR1C3 4192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.