Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.55 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.46 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.46 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13676859 | 1.00 | ALDH1A1 (0.61) | ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G | |
| SCHEMBL3620395 | 1.00 | ALDH1A1 (0.61) | ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G | |
| SCHEMBL15987842 | 0.86 | ALDH1A1 (0.62) | ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G | |
| SCHEMBL25559638 | 0.86 | ALDH1A1 (0.58) | ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G | |
| SCHEMBL15987975 | 0.86 | ALDH1A1 (0.62) | ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G | |
| SCHEMBL3918485 | 0.86 | ALDH1A1 (0.62) | ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G | |
| SCHEMBL8070812 | 0.85 | ALDH1A1 (0.75) | ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G | |
| SCHEMBL10519642 | 0.85 | ALDH1A1 (0.65) | ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G | |
| SCHEMBL1617883 | 0.84 | ALDH1A1 (0.60) | ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G | |
| SCHEMBL1617105 | 0.83 | ALDH1A1 (0.49) | ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9402824-B2 | 9,10-α, α-OH-taxane analogs and methods for production thereof | TAPESTRY PHARMACEUTICALS, INC. (US) | 2016-08-02 | — | — | US | disclosed |
| US-9402824-B2 | 9,10-α, α-OH-taxane analogs and methods for production thereof | TAPESTRY PHARMACEUTICALS, INC. (US) | 2016-08-02 | — | — | US | disclosed |
| US-20150133536-A1 | 9, 10-Alpha, Alpha-OH-Taxane Analogs and Methods for Production Thereof | TAPESTRY PHARMACEUTICALS, INC. (US) | 2015-05-14 | — | — | US | disclosed |
| US-20150133536-A1 | 9, 10-Alpha, Alpha-OH-Taxane Analogs and Methods for Production Thereof | TAPESTRY PHARMACEUTICALS, INC. (US) | 2015-05-14 | — | — | US | disclosed |
| US-8962870-B2 | 9, 10-α, α-OH-taxane analogs and methods for production thereof | TAPESTRY PHARMACEUTICALS, INC. (US) | 2015-02-24 | — | — | US | disclosed |
| US-20120077871-A1 | 9, 10-Alpha, Alpha-OH-Taxane Analogs and Methods for Production Thereof | TAPESTRY PHARMACEUTICALS, INC. (US) | 2012-03-29 | — | — | US | disclosed |
| US-20120077871-A1 | 9, 10-Alpha, Alpha-OH-Taxane Analogs and Methods for Production Thereof | TAPESTRY PHARMACEUTICALS, INC. (US) | 2012-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120077871-A1 | 9, 10-Alpha, Alpha-OH-Taxane Analogs and Methods for Production Thereof | TECR, ADCY9, AKR1C3 | ALDH1A1 447/4885LMNA 1177/4885KDM4E 4743/4885 |
| US-20150133536-A1 | 9, 10-Alpha, Alpha-OH-Taxane Analogs and Methods for Production Thereof | TECR, ADCY9, AKR1C3 | ALDH1A1 447/4885LMNA 1177/4885KDM4E 4743/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.