Sugi Predict

Sugi Predict / Compounds / SCHEMBL3918485

SCHEMBL3918485

SCHEMBL3918485

CC(O)COC1CC(C)CCC1C(C)C

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 4/20 0.62
▸ LMNA P02545 2/20 0.62
▸ KDM4E B2RXH2 1/20 0.59
▸ APOBEC3A P31941 1/20 0.59
▸ APOBEC3G Q9HC16 1/20 0.59
▸ GAA P10253 1/20 0.58
▸ MEN1 O00255 2/20 0.56
▸ KMT2A Q03164 2/20 0.56
▸ NTSR1 P30989 1/20 0.53
▸ NPSR1 Q6W5P4 1/20 0.53
▸ MAPT P10636 1/20 0.51
▸ CYP1A2 P05177 1/20 0.50
▸ CYP2D6 P10635 1/20 0.50
▸ CYP2C9 P11712 1/20 0.50
▸ XBP1 P17861 1/20 0.50
▸ CYP2C19 P33261 1/20 0.50
▸ TRPA1 O75762 2/20 0.47
▸ TRPM8 Q7Z2W7 2/20 0.47
▸ CYP19A1 P11511 2/20 0.46
▸ P2RX4 Q99571 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15987975 1.00 ALDH1A1 (0.62) ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G
SCHEMBL15987842 1.00 ALDH1A1 (0.62) ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G
SCHEMBL1617610 0.87 LMNA (0.56) ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G
SCHEMBL10028337 0.86 ALDH1A1 (0.61) ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G
SCHEMBL13676859 0.86 ALDH1A1 (0.61) ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G
SCHEMBL3620395 0.86 ALDH1A1 (0.61) ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G
SCHEMBL15144383 0.85 LMNA (0.65) ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G
SCHEMBL6421580 0.85 LMNA (0.65) ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G
SCHEMBL17082878 0.85 LMNA (0.65) ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G
SCHEMBL110177 0.85 LMNA (0.65) ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250163006-A1 New Coolants, and Preparations Containing Same SYMRISE AG (DE) 2025-05-22 — — US claimed
US-20250066320-A1 Active Ingredients with Sialagogue and Tingling/Fizzy Effect, and Preparations Containing Same SYMRISE AG (DE) 2025-02-27 — — US claimed
WO-2025026525-A1 HETEROCYCLIC COMPOUNDS AS PHYSIOLOGICAL COOLANTS SYMRISE AG (DE) 2025-02-06 — — WO claimed
EP-4469439-A1 NEW COOLANTS, AND PREPARATIONS CONTAINING SAME Symrise AG (DE) 2024-12-04 — — EP claimed
CN-118984825-A Novel cooling agent and preparation containing same 西姆莱斯股份公司 2024-11-19 — — CN claimed
EP-4452941-A1 ACTIVE INGREDIENTS WITH SIALAGOGUE AND TINGLING/FIZZY EFFECT, AND PREPARATIONS CONTAINING SAME Symrise AG (DE) 2024-10-30 — — EP claimed
US-20240058259-A1 COMPOSITIONS COMPRISING ESSENTIAL OILS FIRMENICH SA (CH) 2024-02-22 — — US claimed
CN-117486690-A Method for preparing cooling agent 3-L-menthoxy-1, 2-propanediol by solvent-free reaction 安徽丰乐香料有限责任公司 2024-02-02 — — CN claimed
US-20240000746-A1 New Cooling Agents and Preparations Containing Them SYMRISE AG (DE) 2024-01-04 — — US claimed
EP-4247791-A2 NEW COOLANTS, AND PREPARATIONS CONTAINING SAME Symrise AG (DE) 2023-09-27 — — EP claimed
WO-2022105986-A1 NOVEL COOLING AGENTS AND PREPARATIONS CONTAINING SAME SYMRISE AG (DE) 2022-05-27 — — WO claimed
US-20200188289-A1 COMPOSITIONS COMPRISING ESSENTIAL OILS FIRMENICH SA (CH) 2020-06-18 — — US claimed
EP-3624757-A1 COMPOSITIONS COMPRISING ESSENTIAL OILS Firmenich SA (CH) 2020-03-25 — — EP claimed
CN-110621287-A Composition comprising essential oils 弗门尼舍有限公司 2019-12-27 — — CN claimed
US-10392371-B2 Compounds useful as modulators of TRPM8 SENOMYX, INC. (US) 2019-08-27 — — US claimed
WO-2018211420-A1 COMPOSITIONS COMPRISING ESSENTIAL OILS FIRMENICH SA (CH) 2018-11-22 — — WO claimed
US-20150087856-A1 MELANIN PRODUCTION INHIBITOR TAKASAGO INTERNATIONAL CORPORATION (JP) 2015-03-26 — — US claimed
US-20140328771-A1 METHOD FOR PRODUCING 3-MENTHOXY PROPANOL AND COMPOSITIONS FOR IMPARTING COOLING SENSATION TAKASAGO INTERNATIONAL CORPORATION (JP) 2014-11-06 — — US claimed
EP-2772477-A1 METHOD FOR PRODUCING 3-MENTHOXY PROPANOL AND COMPOSITION FOR IMPARTING COOLING SENSATION Takasago International Corporation (JP) 2014-09-03 — — EP claimed
US-6491043-B2 Ultra-low particle semiconductor cleaner SCD MOUNTAIN VIEW, INC. 2002-12-10 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10392371-B2 Compounds useful as modulators of TRPM8 TRPM8, TRPM4, TRPM6 ALDH1A1 3726/4885LMNA 3784/4885KDM4E 4171/4885
US-20250066320-A1 Active Ingredients with Sialagogue and Tingling/Fizzy Effect, and Preparations Containing Same TAS2R5, TAS2R7, TAS2R8 ALDH1A1 2893/4885LMNA 4817/4885KDM4E 4202/4885
US-20240000746-A1 New Cooling Agents and Preparations Containing Them TTPA, TREH, TAS2R45 ALDH1A1 1658/4885LMNA 2062/4885KDM4E 3831/4885
US-20140328771-A1 METHOD FOR PRODUCING 3-MENTHOXY PROPANOL AND COMPOSITIONS FOR IMPARTING COOLING SENSATION TRPV1, TRPV3, HMOX2 ALDH1A1 653/4885LMNA 4769/4885KDM4E 4419/4885
US-20250163006-A1 New Coolants, and Preparations Containing Same TTR, TAS2R5, TAS2R50 ALDH1A1 811/4885LMNA 3005/4885KDM4E 4049/4885
US-20150087856-A1 MELANIN PRODUCTION INHIBITOR TYR, MITF, MC1R ALDH1A1 926/4885LMNA 4533/4885KDM4E 242/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.