Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A1 | P13866 | 2/20 | 0.53 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 3/20 | 0.47 |
| ▸ | PPARD | Q03181 | 2/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Uvaretin SCHEMBL30291876 | 0.91 | MAPT (0.56) | SLC5A1SLC5A2MAPTGAACYP19A1 | |
| Uvaretin SCHEMBL4743874 | 0.91 | MAPT (0.56) | SLC5A1SLC5A2MAPTGAACYP19A1 | |
| SCHEMBL28830888 | 0.85 | MAPT (0.53) | SLC5A1SLC5A2MAPTGAACYP19A1 | |
| Diuvaretin SCHEMBL15474801 | 0.83 | KCNA3 (0.52) | SLC5A1SLC5A2MAPTGAAALOX5 | |
| SCHEMBL31237236 | 0.83 | SLC5A1 (0.51) | SLC5A1SLC5A2MAPTGAACYP19A1 | |
| Diuvaretin SCHEMBL31237320 | 0.83 | KCNA3 (0.52) | SLC5A1SLC5A2MAPTGAAALOX5 | |
| SCHEMBL14400965 | 0.81 | FASN (0.67) | SLC5A1SLC5A2MAPTGAACYP19A1 | |
| SCHEMBL28110753 | 0.81 | SLC5A1 (0.57) | SLC5A1SLC5A2MAPTGAACYP19A1 | |
| SCHEMBL1938569 | 0.78 | SLC5A1 (0.73) | SLC5A1SLC5A2MAPTGAACYP19A1 | |
| SCHEMBL17547636 | 0.77 | SLC5A1 (0.58) | SLC5A1SLC5A2MAPTGAACYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120040916-A1 | MOLECULAR INHIBITORS OF THE WNT/BETA-CATENIN PATHWAY | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2012-02-16 | — | — | US | disclosed |
| US-20120040916-A1 | MOLECULAR INHIBITORS OF THE WNT/BETA-CATENIN PATHWAY | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2012-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120040916-A1 | MOLECULAR INHIBITORS OF THE WNT/BETA-CATENIN PATHWAY | WNT1, CTNNB1, WNT3A | SLC5A1 482/4885SLC5A2 385/4885MAPT 1720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.