Sugi Predict

Sugi Predict / Compounds / SCHEMBL1938569

SCHEMBL1938569

SCHEMBL1938569

COc1cc(O)cc(O)c1C(=O)CCc1ccccc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SLC5A1 P13866 8/20 0.73
▸ SLC5A2 P31639 7/20 0.73
▸ MAPT P10636 4/20 0.73
▸ GAA P10253 3/20 0.73
▸ CYP19A1 P11511 3/20 0.65
▸ NFKB1 P19838 2/20 0.59
▸ NFKB2 Q00653 2/20 0.59
▸ RELA Q04206 2/20 0.59
▸ CBS P35520 1/20 0.58
▸ MEN1 O00255 4/20 0.57
▸ KMT2A Q03164 4/20 0.57
▸ HPGD P15428 2/20 0.57
▸ KDM4E B2RXH2 1/20 0.57
▸ SLC16A3 O15427 1/20 0.57
▸ ALDH1A1 P00352 1/20 0.57
▸ LMNA P02545 1/20 0.57
▸ TTR P02766 1/20 0.57
▸ ESR1 P03372 1/20 0.57
▸ TP53 P04637 1/20 0.57
▸ CYP1A2 P05177 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29435841 0.92 NFKB1 (0.68) SLC5A1SLC5A2MAPTGAACYP19A1
SCHEMBL1937964 0.92 NFKB1 (0.68) SLC5A1SLC5A2MAPTGAACYP19A1
SCHEMBL799745 0.90 SLC5A1 (0.72) SLC5A1SLC5A2MAPTGAACYP19A1
SCHEMBL1938352 0.89 SLC5A1 (0.84) SLC5A1SLC5A2MAPTGAACYP19A1
SCHEMBL4742840 0.85 NFKB1 (0.80) SLC5A1SLC5A2MAPTGAACYP19A1
SCHEMBL455029 0.85 SLC5A1 (1.00) SLC5A1SLC5A2MAPTGAACYP19A1
SCHEMBL1726651 0.85 SLC5A1 (0.63) SLC5A1SLC5A2MAPTGAACYP19A1
SCHEMBL17502354 0.82 RAB9A (0.60) SLC5A1SLC5A2MAPTGAANFKB1
SCHEMBL17547636 0.82 SLC5A1 (0.58) SLC5A1SLC5A2MAPTGAACYP19A1
SCHEMBL2282039 0.82 NFKB1 (0.83) SLC5A1SLC5A2MAPTGAACYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2320726-B1 USE OF A MYRICA GALE PLANT FOR THE PRODUCTION OF AN HERBICIDAL AGENT. UNIVERSITÉ CLAUDE BERNARD LYON I (FR) 2017-03-08 — — EP claimed
US-8734858-B2 Use of a myrica gale plant for producing a herbicide agent UNIVERSITE CLAUDE BERNARD LYON I (FR) 2014-05-27 — — US claimed
US-20110201503-A1 USE OF A MYRICA GALE PLANT FOR PRODUCING A HERBICIDE AGENT UNIVERSITE CLAUDE BERNARD LYON I (FR) 2011-08-18 — — US claimed
CN-122005634-A Compound antibacterial gel of herba Pileae Scriptae, and preparation method and application thereof 贵州盛世泰合医药科技有限公司 2026-05-12 — — CN disclosed
US-20250327100-A1 Strain of Pseudomonas Putida Genetically Modified to Express a Benzalacetone Reductase BGENE GENETICS (FR) 2025-10-23 — — US disclosed
CN-119080851-A Macrocyclic polyphenol compound, preparation method thereof and application thereof in preparing cholestasis type liver injury medicines 上海中医药大学 2024-12-06 — — CN disclosed
WO-2024189607-A1 METHODS AND BIOAVAILABLE HIGHLY PERMEABLE COMPOUNDS FOR DISEASES TREATMENT DIDENKO KIRILL (MX) 2024-09-19 — — WO disclosed
EP-4370674-A1 STRAIN OF PSEUDOMONAS PUTIDA GENETICALLY MODIFIED TO EXPRESS A BENZALACETONE REDUCTASE BGene Genetics (FR) 2024-05-22 — — EP disclosed
WO-2023285763-A1 STRAIN OF PSEUDOMONAS PUTIDA GENETICALLY MODIFIED TO EXPRESS A BENZALACETONE REDUCTASE BGENE GENETICS (FR) 2023-01-19 — — WO disclosed
EP-2888012-B1 ORAL CARE UNIV PRETORIA (ZA) 2020-06-17 — — EP disclosed
CN-103948736-B The compound Chinese medicinal preparation for the treatment of hepatocarcinoma and production method thereof 张树球 2016-10-12 — — CN disclosed
US-20150174059-A1 ORAL CARE UNIVERSITY OF PRETORIA (ZA) 2015-06-25 — — US disclosed
US-9061984-B2 Compounds related to chalcones and benzothienopyrimidines, their synthesis, and uses to treat diseases UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (US) 2015-06-23 — — US disclosed
CN-103948736-A Chinese herbal medicine compound preparation for treating liver cancer and production method thereof ZHANG SHUQIU 2014-07-30 — — CN disclosed
US-8734858-B2 Use of a myrica gale plant for producing a herbicide agent UNIVERSITE CLAUDE BERNARD LYON I (FR) 2014-05-27 — — US disclosed
WO-2014033625-A2 ORAL CARE UNIVERSITY OF PRETORIA (ZA) 2014-03-06 — — WO disclosed
US-20110201503-A1 USE OF A MYRICA GALE PLANT FOR PRODUCING A HERBICIDE AGENT UNIVERSITE CLAUDE BERNARD LYON I (FR) 2011-08-18 — — US disclosed
US-20110190325-A1 COMPOUNDS, THEIR SYNTHESES, AND THIER USES THE JOHNS HOPKINS UNIVERSITY 2011-08-04 — — US disclosed
EP-2330906-A1 COMPOUNDS, THEIR SYNTHESES, AND THEIR USES University Of Louisville Research Foundation, Inc. (US) 2011-06-15 — — EP disclosed
WO-2010019861-A1 COMPOUNDS, THEIR SYNTHESES, AND THEIR USES UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (US) 2010-02-18 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150174059-A1 ORAL CARE NOP2, POLR1C, DPM1 SLC5A1 4623/4885SLC5A2 4424/4885MAPT 2090/4885
US-20110201503-A1 USE OF A MYRICA GALE PLANT FOR PRODUCING A HERBICIDE AGENT MGAM, GALC, MGAM2 SLC5A1 459/4885SLC5A2 279/4885MAPT 1384/4885
US-20110190325-A1 COMPOUNDS, THEIR SYNTHESES, AND THIER USES TERT, TYMS, NISCH SLC5A1 1429/4885SLC5A2 956/4885MAPT 2194/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.