SCHEMBL10028740

SCHEMBL10028740

CCC(C)(C)C(=O)c1ccc(Oc2ccc(C(=O)C(C)(C)CC)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.50
RAB9A P51151 3/20 0.50
MAPT P10636 2/20 0.50
SMN1; SMN2 Q16637 3/20 0.46
ALDH1A1 P00352 3/20 0.46
ELANE P08246 2/20 0.46
TSHR P16473 1/20 0.46
HTT P42858 1/20 0.46
PARP10 Q53GL7 5/20 0.45
PARP15 Q460N3 2/20 0.45
KMT2A Q03164 1/20 0.45
PARP14 Q460N5 1/20 0.45
PARP16 Q8N5Y8 1/20 0.45
PARP11 Q9NR21 1/20 0.45
PARP4 Q9UKK3 1/20 0.45
NPC1 O15118 2/20 0.44
POLB P06746 1/20 0.44
CYP2C9 P11712 1/20 0.44
ESRRA P11474 1/20 0.41
PPARA Q07869 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12472613 0.93 PARP15 (0.51) HPGDRAB9AMAPTTSHRPARP10
SCHEMBL11530017 0.93 PARP10 (0.51) HPGDRAB9ASMN1; SMN2ALDH1A1PARP10
SCHEMBL13313737 0.93 HPGD (0.44) HPGDRAB9AMAPTSMN1; SMN2ALDH1A1
SCHEMBL12948138 0.88 MLYCD (0.42) ALDH1A1ELANEKMT2A
SCHEMBL21237888 0.87 ELANE (0.46) HPGDRAB9AMAPTSMN1; SMN2ALDH1A1
SCHEMBL6613084 0.87 CES2 (0.53) RAB9AMAPTALDH1A1ELANEPARP10
SCHEMBL21577561 0.86 HPGD (0.39) HPGDRAB9AMAPTSMN1; SMN2ALDH1A1
SCHEMBL12164640 0.85 ELANE (0.41) MAPTSMN1; SMN2ALDH1A1ELANETSHR
SCHEMBL21237992 0.85 HPGD (0.50) HPGDRAB9AMAPTSMN1; SMN2ALDH1A1
SCHEMBL12948130 0.84 ELANE (0.41) MAPTSMN1; SMN2ALDH1A1ELANETSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220128913-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2022-04-28 US disclosed
US-20210286277-A1 UNDERCOAT LAYER, METHOD FOR MANUFACTURING UNDERCOAT LAYER, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND IMAGE FORMING APPARATUS KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2021-09-16 US disclosed
US-10996575-B2 Electrophotographic photosensitive member, process cartridge, and image forming apparatus KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2021-05-04 US disclosed
US-20200233324-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2020-07-23 US disclosed
US-20200233321-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2020-07-23 US disclosed
US-20200231535-A1 TERPHENYL COMPOUND, ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, AND METHOD FOR PRODUCING TERPHENYL COMPOUND KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2020-07-23 US disclosed
US-20200117106-A1 COMPOUND MIXTURE, ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER AND PRODUCTION METHOD FOR COMPOUND MIXTURE KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2020-04-16 US disclosed
US-10379451-B2 Polyarylate resin and electrophotographic photosensitive member KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2019-08-13 US disclosed
US-10359713-B2 Electrophotographic photosensitive member, process cartridge, and image forming apparatus KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2019-07-23 US disclosed
US-8192645-B2 Liquid crystal polyester resin composition for camera module JX NIPPON OIL & ENERGY CORPORATION (JP) 2012-06-05 US disclosed
US-20110089371-A1 LIQUID CRYSTAL POLYESTER RESIN COMPOSITION FOR CAMERA MODULE JX NIPPON OIL & ENERGY CORPORATION (JP) 2011-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200231535-A1 TERPHENYL COMPOUND, ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, AND METHOD FOR PRODUCING TERPHENYL COMPOUND ABCB1, TERB1, PAH HPGD 2351/4885RAB9A 937/4885MAPT 2083/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.