Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | BCL2 | P10415 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | ELANE | P08246 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.35 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.35 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.35 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10046303 | 0.91 | LMNA (0.38) | ALDH1A1HTTLMNA | |
| SCHEMBL10028740 | 0.86 | HPGD (0.50) | HPGDRAB9AMAPTNPC1POLB | |
| SCHEMBL24263661 | 0.81 | GABBR2 (0.36) | RAB9ANPC1CYP2C9ALDH1A1SMN1; SMN2 | |
| SCHEMBL13313737 | 0.80 | HPGD (0.44) | HPGDRAB9AMAPTNPC1POLB | |
| SCHEMBL12472613 | 0.80 | PARP15 (0.51) | HPGDRAB9AMAPTNPC1POLB | |
| SCHEMBL21165790 | 0.80 | PARP10 (0.54) | ALDH1A1SMN1; SMN2HTTSLC2A1PARP10 | |
| SCHEMBL11530017 | 0.80 | PARP10 (0.51) | HPGDRAB9ANPC1POLBCYP2C9 | |
| SCHEMBL12305922 | 0.79 | KMT2A (0.42) | MAPTPOLBALDH1A1SMN1; SMN2ELANE | |
| SCHEMBL12948131 | 0.78 | KDM4E (0.43) | LMNA | |
| SCHEMBL13178834 | 0.78 | HRH3 (0.39) | HPGDRAB9AMAPTCYP2C9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10649351-B2 | Electrophotographic photosensitive member, process cartridge, and image forming apparatus | KYOCERA DOCUMENT SOLUTIONS INC. (JP) | 2020-05-12 | — | — | US | disclosed |
| US-20190354027-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS | KYOCERA DOCUMENT SOLUTIONS INC. (JP) | 2019-11-21 | — | — | US | disclosed |