Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | MTOR | P42345 | 1/20 | 0.54 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11592029 | 0.82 | RAB9A (0.52) | RAB9AMTORGRM7CYP3A4ALOX15 | |
| SCHEMBL27539055 | 0.81 | RAB9A (0.60) | RAB9AMTORGRM7CYP3A4ALOX15 | |
| SCHEMBL1780965 | 0.81 | AKT1 (0.47) | LMNAAOC3 | |
| SCHEMBL1573478 | 0.80 | MTOR (0.54) | RAB9AMTORGRM7CYP3A4ALOX15 | |
| SCHEMBL9728971 | 0.79 | AOC3 (0.52) | CYP3A4ALOX15TSHRALDH1A1LMNA | |
| SCHEMBL31000817 | 0.78 | MTOR (0.52) | RAB9AMTORGRM7CYP3A4ALOX15 | |
| SCHEMBL28512852 | 0.78 | MTOR (0.52) | RAB9AMTORGRM7CYP3A4ALOX15 | |
| SCHEMBL20049938 | 0.77 | CYP2D6 (0.69) | RAB9AALDH1A1ABCB1ADRB3ADRB2 | |
| SCHEMBL15591917 | 0.76 | GRM7 (0.65) | RAB9AMTORGRM7CYP3A4ALOX15 | |
| Iodomethane SCHEMBL1573608 | 0.76 | MTOR (0.48) | RAB9AMTORGRM7CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8207355-B2 | Method for preparing azetidine derivatives | SANOFI-AVENTIS (FR) | 2012-06-26 | — | — | US | disclosed |
| US-20110118481-A1 | METHOD FOR PREPARING AZETIDINE DERIVATIVES | SANOFI-AVENTIS (FR) | 2011-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110118481-A1 | METHOD FOR PREPARING AZETIDINE DERIVATIVES | QDPR, AZI2, NISCH | RAB9A 52/4885MTOR 2159/4885GRM7 4785/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.