SCHEMBL100291

SCHEMBL100291

CCCCCCCCC(CC[CH]CCC(CCCCCCCC)CCCCCCCC)CCCCCCC

nearest known ligand 0.52

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.52
ADH1B P00325 1/20 0.43
ADH1C P00326 1/20 0.43
ADH1A P07327 1/20 0.43
ADH4 P08319 1/20 0.43
ADH7 P40394 1/20 0.43
DNM1 Q05193 5/20 0.40
TSHR P16473 3/20 0.40
THRB P10828 1/20 0.40
OPRM1 P35372 1/20 0.39
GPR84 Q9NQS5 2/20 0.37
FDPS P14324 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9784135 0.95 LMNA (0.48) LMNAADH1BADH1CADH1AADH4
SCHEMBL7105674 0.93 LMNA (0.44) LMNAADH1BADH1CADH1AADH4
SCHEMBL2484622 0.88 ACE2 (0.43) LMNAADH1BADH1CADH1AADH4
SCHEMBL5265163 0.88 ACE2 (0.43) LMNAADH1BADH1CADH1AADH4
SCHEMBL2485361 0.88 ACE2 (0.43) LMNAADH1BADH1CADH1AADH4
SCHEMBL4034493 0.88 ACE2 (0.43) LMNAADH1BADH1CADH1AADH4
SCHEMBL7176175 0.86 TSHR (0.41) LMNAADH1BADH1CADH1AADH4
SCHEMBL27917250 0.85 ALDH1A1 (0.41) LMNAADH1BADH1CADH1AADH4
SCHEMBL11297211 0.84 LMNA (0.41) LMNAADH1BADH1CADH1AADH4
SCHEMBL9304796 0.84 LMNA (0.46) LMNAADH1BADH1CADH1AADH4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2601166-A1 COSMETIC PREPARATIONS Cognis IP Management GmbH (DE) 2013-06-12 EP disclosed
EP-2426101-A1 Cosmetic preparations Cognis IP Management GmbH (DE) 2012-03-07 EP disclosed
WO-2012016642-A1 COSMETIC PREPARATIONS COGNIS IP MANAGEMENT GMBH (DE) 2012-02-09 WO disclosed