Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.37 |
| ▸ | FAAH | O00519 | 2/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | ADH1B | P00325 | 1/20 | 0.36 |
| ▸ | ADH1C | P00326 | 1/20 | 0.36 |
| ▸ | ADH1A | P07327 | 1/20 | 0.36 |
| ▸ | ADH4 | P08319 | 1/20 | 0.36 |
| ▸ | ADH7 | P40394 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | TOP1 | P11387 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4496245 | 0.91 | LMNA (0.43) | TSHRLMNADNM1FAAHTRPV1 | |
| SCHEMBL9784135 | 0.91 | LMNA (0.48) | TSHRLMNADNM1FAAHTRPV1 | |
| SCHEMBL9304796 | 0.89 | LMNA (0.46) | TSHRLMNADNM1FAAHTRPV1 | |
| SCHEMBL9301472 | 0.86 | TSHR (0.41) | TSHRLMNADNM1FAAHTRPV1 | |
| SCHEMBL11348860 | 0.86 | TSHR (0.41) | TSHRLMNADNM1FAAHTRPV1 | |
| SCHEMBL100291 | 0.86 | LMNA (0.52) | TSHRLMNADNM1ADH1BADH1C | |
| SCHEMBL7105674 | 0.84 | LMNA (0.44) | TSHRLMNADNM1ADH1BADH1C | |
| SCHEMBL4197569 | 0.84 | ACE2 (0.35) | TSHRADH1BADH1CADH1AADH4 | |
| SCHEMBL23673217 | 0.83 | ALDH1A1 (0.45) | TSHRLMNADNM1FAAHTRPV1 | |
| SCHEMBL27917250 | 0.81 | ALDH1A1 (0.41) | TSHRLMNADNM1ADH1BADH1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1000070-B1 | SILICON-CONTAINING CHAIN EXTENDERS | AORTECH BIOMATERIALS PTY LTD (AU) | 2003-09-10 | — | — | EP | claimed |