Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | UBE2N | P61088 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.36 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10062798 | 0.84 | KCNN4 (0.45) | ALDH1A1LMNAHTTKCNN4SMN1; SMN2 | |
| SCHEMBL12114460 | 0.82 | KCNN4 (0.43) | ALDH1A1LMNAHTTKCNN4SMN1; SMN2 | |
| SCHEMBL10029127 | 0.78 | ALDH1A1 (0.41) | ALDH1A1LMNAHTTSMN1; SMN2KIF11 | |
| SCHEMBL14559172 | 0.78 | TDP1 (0.40) | ALDH1A1LMNAHTTSMN1; SMN2KMT2A | |
| SCHEMBL12114459 | 0.74 | KIF11 (0.41) | ALDH1A1LMNAHTTSMN1; SMN2KIF11 | |
| SCHEMBL3811027 | 0.74 | ALDH1A1 (0.40) | ALDH1A1LMNAHTTSMN1; SMN2KMT2A | |
| SCHEMBL17381237 | 0.74 | ALDH1A1 (0.40) | ALDH1A1LMNAHTTSMN1; SMN2KMT2A | |
| SCHEMBL6912176 | 0.74 | FFAR1 (0.47) | ALDH1A1SMN1; SMN2KMT2AL3MBTL1MEN1 | |
| SCHEMBL12117596 | 0.73 | KCNN4 (0.43) | ALDH1A1LMNAHTTKCNN4SMN1; SMN2 | |
| SCHEMBL10029128 | 0.73 | POLB (0.42) | ALDH1A1SMN1; SMN2KMT2AGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8741951-B2 | Non-steroidal compounds for androgen receptor modulation | CNR—Consiglio Nazionale Delle Ricerche (IT) | 2014-06-03 | — | — | US | disclosed |
| US-20120041046-A1 | NON-STEROIDAL COMPOUNDS FOR ANDROGEN RECEPTOR MODULATION | CNR - CONSIGLIO NAZIONALE DELLE RICERCHE (IT) | 2012-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120041046-A1 | NON-STEROIDAL COMPOUNDS FOR ANDROGEN RECEPTOR MODULATION | NR5A1, AR, SHBG | ALDH1A1 810/4885LMNA 4318/4885HTT 4825/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.