SCHEMBL10029283

SCHEMBL10029283

c1cc(-c2ccccc2-c2cccc3c2sc2ccccc23)cc(-n2c3ccccc3c3ccccc32)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.49
PARP14 Q460N5 1/20 0.40
KDM4E B2RXH2 1/20 0.40
ATM Q13315 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
PRKDC P78527 7/20 0.39
PIK3CD O00329 2/20 0.38
PIK3CB P42338 2/20 0.38
BRD4 O60885 1/20 0.38
PIK3CA P42336 1/20 0.38
MTOR P42345 1/20 0.38
PIK3CG P48736 1/20 0.38
KCNH2 Q12809 1/20 0.38
BRDT Q58F21 1/20 0.38
MAPT P10636 3/20 0.36
RXFP1 Q9HBX9 1/20 0.36
TNKS O95271 1/20 0.35
TNKS2 Q9H2K2 1/20 0.35
TP53 P04637 1/20 0.34
GPR3 P46089 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21152357 0.95 ALOX5 (0.55) ALOX5PARP14KDM4EATML3MBTL1
SCHEMBL1687809 0.92 ALOX5 (0.52) ALOX5PARP14KDM4EATML3MBTL1
SCHEMBL1687711 0.92 ALOX5 (0.52) ALOX5PARP14KDM4EATML3MBTL1
SCHEMBL1687803 0.92 ALOX5 (0.52) ALOX5PARP14KDM4EATML3MBTL1
SCHEMBL18381746 0.91 ALOX5 (0.51) ALOX5PARP14KDM4EATML3MBTL1
SCHEMBL16674292 0.91 ALOX5 (0.51) ALOX5PARP14KDM4EATML3MBTL1
SCHEMBL22432349 0.91 ALOX5 (0.47) ALOX5PARP14KDM4EATML3MBTL1
SCHEMBL16409586 0.90 ALOX5 (0.50) ALOX5PARP14KDM4EATML3MBTL1
SCHEMBL14867995 0.90 ALOX5 (0.50) ALOX5PARP14KDM4EATML3MBTL1
SCHEMBL17885354 0.90 ALOX5 (0.53) ALOX5PARP14KDM4EATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9997726-B2 Dibenzothiophene-containing materials in phosphorescent light emitting diodes UNIVERSAL DISPLAY CORPORATION (US) 2018-06-12 US disclosed
US-9997726-B2 Dibenzothiophene-containing materials in phosphorescent light emitting diodes UNIVERSAL DISPLAY CORPORATION (US) 2018-06-12 US disclosed
US-20160372685-A1 Dibenzothiophene-Containing Materials in Phosphorescent Light Emitting Diodes UNIVERSAL DISPLAY CORPORATION (US) 2016-12-22 US disclosed
US-20160372685-A1 Dibenzothiophene-Containing Materials in Phosphorescent Light Emitting Diodes UNIVERSAL DISPLAY CORPORATION (US) 2016-12-22 US disclosed
US-9123903-B2 Dibenzothiophene-containing materials in phosphorescent light emitting diodes UNIVERSAL DISPLAY CORPORATION (US) 2015-09-01 US disclosed
US-9123903-B2 Dibenzothiophene-containing materials in phosphorescent light emitting diodes UNIVERSAL DISPLAY CORPORATION (US) 2015-09-01 US disclosed
US-20140008643-A1 DIBENZOTHIOPHENE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2014-01-09 US disclosed
US-20140008643-A1 DIBENZOTHIOPHENE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2014-01-09 US disclosed
US-8580402-B2 Dibenzothiophene-containing materials in phosphorescent light emitting diodes UNIVERSAL DISPLAY CORPORATION (US) 2013-11-12 US disclosed
US-8580402-B2 Dibenzothiophene-containing materials in phosphorescent light emitting diodes UNIVERSAL DISPLAY CORPORATION (US) 2013-11-12 US disclosed
US-20120012829-A1 DIBENZOTHIOPHENE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2012-01-19 US disclosed
US-20120012829-A1 DIBENZOTHIOPHENE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2012-01-19 US disclosed
US-8007927-B2 Dibenzothiophene-containing materials in phosphorescent light emitting diodes UNIVERSAL DISPLAY CORPORATION (US) 2011-08-30 US disclosed
US-8007927-B2 Dibenzothiophene-containing materials in phosphorescent light emitting diodes UNIVERSAL DISPLAY CORPORATION (US) 2011-08-30 US disclosed
WO-2009085344-A2 DIBENZOTHIOPHENE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2009-07-09 WO disclosed
US-20090167162-A1 DIBENZOTHIOPHENE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2009-07-02 US disclosed
US-20090167162-A1 DIBENZOTHIOPHENE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2009-07-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090167162-A1 DIBENZOTHIOPHENE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTING DIODES DDT, BPNT1, DBF4 ALOX5 1131/4885PARP14 2217/4885KDM4E 3035/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.