SCHEMBL1687803

SCHEMBL1687803

c1cc(-c2cccc(-c3cccc4c3sc3ccccc34)c2)cc(-c2cccc(-n3c4ccccc4c4ccccc43)c2)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.52
KDM4E B2RXH2 1/20 0.40
ATM Q13315 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
PRKDC P78527 7/20 0.40
PARP14 Q460N5 1/20 0.38
MAPT P10636 3/20 0.36
RXFP1 Q9HBX9 1/20 0.36
PIK3CD O00329 2/20 0.35
PIK3CB P42338 2/20 0.35
BRD4 O60885 1/20 0.35
PIK3CA P42336 1/20 0.35
MTOR P42345 1/20 0.35
PIK3CG P48736 1/20 0.35
KCNH2 Q12809 1/20 0.35
BRDT Q58F21 1/20 0.35
TNKS O95271 1/20 0.35
TNKS2 Q9H2K2 1/20 0.35
TP53 P04637 1/20 0.34
DNPH1 O43598 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1687809 1.00 ALOX5 (0.52) ALOX5KDM4EATML3MBTL1PRKDC
SCHEMBL1687711 1.00 ALOX5 (0.52) ALOX5KDM4EATML3MBTL1PRKDC
SCHEMBL18381746 0.99 ALOX5 (0.51) ALOX5KDM4EATML3MBTL1PRKDC
SCHEMBL21152357 0.97 ALOX5 (0.55) ALOX5KDM4EATML3MBTL1PRKDC
SCHEMBL1687693 0.95 ALOX5 (0.48) ALOX5KDM4EATML3MBTL1PRKDC
SCHEMBL17038445 0.95 ALOX5 (0.48) ALOX5KDM4EATML3MBTL1PRKDC
SCHEMBL1687787 0.95 ALOX5 (0.48) ALOX5KDM4EATML3MBTL1PRKDC
SCHEMBL17038401 0.95 ALOX5 (0.48) ALOX5KDM4EATML3MBTL1PRKDC
SCHEMBL1687788 0.95 ALOX5 (0.48) ALOX5KDM4EATML3MBTL1PRKDC
SCHEMBL1687754 0.95 ALOX5 (0.48) ALOX5KDM4EATML3MBTL1PRKDC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9401482-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2016-07-26 US disclosed
US-9401482-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2016-07-26 US disclosed
US-9067947-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2015-06-30 US disclosed
US-20150097176-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-04-09 US disclosed
US-20150097176-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-04-09 US disclosed
US-8932734-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2015-01-13 US disclosed
US-8932734-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2015-01-13 US disclosed
US-20120086329-A1 Novel 3, 9-Linked Oliogocarbazole-Based Hosts, Containing DBT and DBF Fragments, Separated by Aromatic Spacers Universal Disolay Corporation (US) 2012-04-12 US disclosed
US-20120086329-A1 Novel 3, 9-Linked Oliogocarbazole-Based Hosts, Containing DBT and DBF Fragments, Separated by Aromatic Spacers Universal Disolay Corporation (US) 2012-04-12 US disclosed
WO-2012048266-A1 NOVEL 3, 9-LINKED OLIGOCARBAZOLE-BASED HOSTS, CONTAINING DBT AND DBR FRAGMENTS, SEPARATED BY AROMATIC SPACERS UNIVERSAL DISPLAY CORPORATION (US) 2012-04-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120086329-A1 Novel 3, 9-Linked Oliogocarbazole-Based Hosts, Containing DBT and DBF Fragments, Separated by Aromatic Spacers DBF4, OGFOD1, DDT ALOX5 1460/4885KDM4E 1173/4885ATM 1916/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.