Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | SLC13A5 | Q86YT5 | 7/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SLC13A2 | Q13183 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15806369 | 1.00 | MEN1 (0.41) | MEN1HPGDRECQLKMT2AHSD17B10 | |
| SCHEMBL15031322 | 0.86 | L3MBTL1 (0.41) | MEN1HPGDRECQLKMT2AHSD17B10 | |
| SCHEMBL16254847 | 0.86 | L3MBTL1 (0.41) | MEN1HPGDRECQLKMT2AHSD17B10 | |
| SCHEMBL12745455 | 0.84 | L3MBTL1 (0.40) | MEN1HPGDRECQLKMT2AHSD17B10 | |
| SCHEMBL13059735 | 0.81 | MAPT (0.40) | MEN1HPGDRECQLKMT2AHSD17B10 | |
| SCHEMBL14600621 | 0.81 | MAPT (0.40) | MEN1HPGDRECQLKMT2AHSD17B10 | |
| SCHEMBL10029372 | 0.81 | ALDH1A1 (0.56) | L3MBTL1ALDH1A1LMNACYP2D6CYP2C19 | |
| SCHEMBL23331 | 0.80 | ALDH1A1 (0.52) | MEN1HPGDRECQLKMT2AHSD17B10 | |
| SCHEMBL12746071 | 0.80 | L3MBTL1 (0.37) | MEN1HPGDRECQLKMT2AHSD17B10 | |
| SCHEMBL12745724 | 0.79 | HSD17B10 (0.38) | MEN1HPGDRECQLKMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140343039-A1 | PROCESS FOR PREPARING CEPHALOTAXINE ESTERS | ROBIN JEAN-PIERRE (CH) | 2014-11-20 | — | — | US | disclosed |
| US-20140343039-A1 | PROCESS FOR PREPARING CEPHALOTAXINE ESTERS | ROBIN JEAN-PIERRE (CH) | 2014-11-20 | — | — | US | disclosed |
| US-20120022250-A1 | PROCESS FOR PREPARING CEPHALOTAXINE ESTERS | ROBIN JEAN-PIERRE (CH) | 2012-01-26 | — | — | US | disclosed |
| US-20120022250-A1 | PROCESS FOR PREPARING CEPHALOTAXINE ESTERS | ROBIN JEAN-PIERRE (CH) | 2012-01-26 | — | — | US | disclosed |
| WO-2010103405-A2 | PROCESS FOR PREPARING CEPHALOTAXINE ESTERS | ROBIN JEAN-PIERRE (CH) | 2010-09-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120022250-A1 | PROCESS FOR PREPARING CEPHALOTAXINE ESTERS | CHRM1, OPRM1, CHRM2 | MEN1 3409/4885HPGD 2118/4885RECQL 1117/4885 |
| US-20140343039-A1 | PROCESS FOR PREPARING CEPHALOTAXINE ESTERS | CFH, C5, CHRM1 | MEN1 3084/4885HPGD 2297/4885RECQL 1905/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.