SCHEMBL10029693

SCHEMBL10029693

Cc1cccc(C)c1-c1cccc(C(=O)c2cccc(-c3c(C)cccc3C)c2)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B1 P14061 2/20 0.54
HSD17B2 P37059 2/20 0.54
LMNA P02545 2/20 0.51
NPC1 O15118 1/20 0.51
MITF O75030 1/20 0.51
POLB P06746 1/20 0.51
CNR2 P34972 3/20 0.50
CNR1 P21554 1/20 0.50
ATM Q13315 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
FFAR1 O14842 1/20 0.47
PBRM1 Q86U86 1/20 0.46
BRD4 O60885 1/20 0.45
BRD2 P25440 1/20 0.45
CREBBP Q92793 1/20 0.45
MAPT P10636 2/20 0.43
PTGS1 P23219 2/20 0.43
CXCR1 P25024 2/20 0.43
CXCR2 P25025 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2020761 0.86 KMO (0.60) LMNANPC1FFAR1SMN1; SMN2KMO
SCHEMBL4262253 0.86 PARP1 (0.60) POLBTDP1L3MBTL1FFAR1MAPT
SCHEMBL12577690 0.86 BRD4 (0.59) NPC1TDP1FFAR1BRD4BRD2
SCHEMBL15398032 0.82 FFAR1 (0.43) TDP1FFAR1BRD4BRD2CREBBP
SCHEMBL16523465 0.80 GSK3B (0.49) FFAR1BRD4BRD2CREBBPGRIA1
SCHEMBL2022466 0.79 POLB (0.56) NPC1POLBMAPTSMN1; SMN2ALDH1A1
SCHEMBL10296106 0.78 LMNA (0.55) HSD17B1HSD17B2LMNANPC1MITF
SCHEMBL10039253 0.78 CNR2 (0.49) HSD17B1HSD17B2CNR2CNR1FFAR1
SCHEMBL28452076 0.78 NR1H4 (0.59) HSD17B1HSD17B2LMNACNR2CNR1
SCHEMBL12565770 0.78 HTR7 (0.53) FFAR1BRD4CYP3A4ALDH1A1GRIA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8206839-B2 Light-emitting layer between electrodes including luminescent material, e.g.,bis(m-triphenylsilyl)phenyl)carbonyl; excited triplet energy levels of the compounds is 65-95 kcal/mol; glass transition temperature 130-400 degrees C.; low driving voltage; durability; efficiency; displays; optics; dyes FUJIFILM CORPORATION (JP) 2012-06-26 US disclosed
US-8206839-B2 Light-emitting layer between electrodes including luminescent material, e.g.,bis(m-triphenylsilyl)phenyl)carbonyl; excited triplet energy levels of the compounds is 65-95 kcal/mol; glass transition temperature 130-400 degrees C.; low driving voltage; durability; efficiency; displays; optics; dyes FUJIFILM CORPORATION (JP) 2012-06-26 US disclosed
US-20070077453-A1 Organic electroluminescent element FUJIFILM CORPORATION 2007-04-05 US disclosed
US-20070077453-A1 Organic electroluminescent element FUJIFILM CORPORATION 2007-04-05 US disclosed