Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32669008 | 1.00 | TSHR (0.45) | TSHRALDH1A1PDE4ARECQLLMNA | |
| Butyl Alcohol SCHEMBL28237100 | 0.88 | TSHR (0.36) | TSHRALDH1A1PDE4ARECQLLMNA | |
| SCHEMBL9321565 | 0.85 | PDE4A (0.52) | ALDH1A1PDE4ALMNAMEN1USP2 | |
| SCHEMBL9323008 | 0.85 | PDE4A (0.52) | ALDH1A1PDE4ALMNAMEN1USP2 | |
| SCHEMBL8991473 | 0.85 | PDE4A (0.52) | ALDH1A1PDE4ALMNAMEN1USP2 | |
| SCHEMBL8762542 | 0.83 | PDE4A (0.50) | ALDH1A1PDE4ALMNAMEN1USP2 | |
| SCHEMBL3517475 | 0.83 | PDE4A (0.50) | ALDH1A1PDE4ALMNAMEN1USP2 | |
| SCHEMBL8763289 | 0.83 | PDE4A (0.50) | ALDH1A1PDE4ALMNAMEN1USP2 | |
| SCHEMBL3517791 | 0.83 | PDE4A (0.50) | ALDH1A1PDE4ALMNAMEN1USP2 | |
| SCHEMBL8763069 | 0.83 | PDE4A (0.50) | ALDH1A1PDE4ALMNAMEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 277 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1651199-A4 | METHOD AND PREPARATION FOR REDUCING IRRITATION AND/OR INFLAMMATORY REACTION IN HUMAN SKIN | PCR TECHNOLOGY HOLDINGS LC (US) | 2008-08-20 | — | — | EP | claimed |
| US-20080131386-A1 | Topical product formulations containing strontium for reducing skin irritation | COSMEDERM TECHNOLOGIES, INC. (US) | 2008-06-05 | — | — | US | claimed |
| EP-1651199-A1 | METHOD AND PREPARATION FOR REDUCING IRRITATION AND/OR INFLAMMATORY REACTION IN HUMAN SKIN | PCR Technology Holdings, LC (US) | 2006-05-03 | — | — | EP | claimed |
| US-20050197407-A1 | Method and preparation for reducing irritation and/or inflammatory reaction in human skin | PCR TECHNOLOGY HOLDINGS, LC (US) | 2005-09-08 | — | — | US | claimed |
| WO-2005079775-A1 | METHOD AND PREPARATION FOR REDUCING IRRITATION AND/OR INFLAMMATORY REACTION IN HUMAN SKIN | PCR TECHNOLOGY HOLDINGS, LC (US) | 2005-09-01 | — | — | WO | claimed |
| EP-0801570-B1 | FORMULATIONS AND METHODS FOR REDUCING SKIN IRRITATION | COSMEDERM TECHNOLOGIES (US) | 2004-12-08 | — | — | EP | claimed |
| EP-1136065-B1 | Formulations and methods for reducing skin irritation | COSMEDERM TECHNOLOGIES (US) | 2004-11-24 | — | — | EP | claimed |
| US-20030147975-A1 | Pharmaceutical composition which produces irritation | JOSHI YATINDRA (US) | 2003-08-07 | — | — | US | claimed |
| US-20030124202-A1 | Formulations and methods for reducing skin irritation | SENSORY SYSTEMS | 2003-07-03 | — | — | US | claimed |
| EP-0801554-B1 | FORMULATIONS AND METHODS FOR REDUCING SKIN IRRITATION | COSMEDERM TECHNOLOGIES (US) | 2003-04-16 | — | — | EP | claimed |
| WO-1996019228-A1 | FORMULATIONS AND METHODS FOR REDUCING SKIN IRRITATION | COSMEDERM TECHNOLOGIES (US) | 1996-06-27 | — | — | WO | claimed |
| EP-0338565-B1 | N-Alkoxyalkylamides of hydroxyacids and skin treating compositions therewith | REVLON CONSUMER PROD CORP (US) | 1994-08-10 | — | — | EP | claimed |
| EP-0580453-A2 | Hair-care compositions containing N-alkoxyalkylamides | Revlon Consumer Products Corporation (US) | 1994-01-26 | — | — | EP | claimed |
| US-5139771-A | Hydrolyzed grain product, seaweed derivative, water | REVLON, INC. (US) | 1992-08-18 | — | — | US | claimed |
| US-5084270-A | Moisturizing and/or softening cosmetics for skin treatment | REVLON, INC. (US) | 1992-01-28 | — | — | US | claimed |
| WO-1991000083-A1 | SKIN CARE PREPARATION | REVLON, INC. (US) | 1991-01-10 | — | — | WO | claimed |
| US-4973473-A | Skin care preparation | REVLON, INC. (US) | 1990-11-27 | — | — | US | claimed |
| EP-0366753-A4 | N-ALKOXYALKYLAMIDES AND COSMETIC TREATING COMPOSITIONS THEREWITH. | REVLON (US) | 1990-06-27 | — | — | EP | claimed |
| EP-0366753-A1 | N-ALKOXYALKYLAMIDES AND COSMETIC TREATING COMPOSITIONS THEREWITH | REVLON, INC. (US) | 1990-05-09 | — | — | EP | claimed |
| WO-1989010121-A1 | N-ALKOXYALKYLAMIDES AND COSMETIC TREATING COMPOSITIONS THEREWITH | REVLON, INC. (US) | 1989-11-02 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050197407-A1 | Method and preparation for reducing irritation and/or inflammatory reaction in human skin | IL1B, IL17A, HSD17B7 | TSHR 3549/4885ALDH1A1 1787/4885PDE4A 429/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.