SCHEMBL10030122

SCHEMBL10030122

CCCSC(=S)SC(C)(C)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.41
TDP1 Q9NUW8 1/20 0.39
HDAC3 O15379 2/20 0.32
HDAC4 P56524 2/20 0.32
HDAC1 Q13547 2/20 0.32
HDAC7 Q8WUI4 2/20 0.32
HDAC2 Q92769 2/20 0.32
HDAC10 Q969S8 2/20 0.32
HDAC11 Q96DB2 2/20 0.32
HDAC8 Q9BY41 2/20 0.32
HDAC6 Q9UBN7 2/20 0.32
HDAC9 Q9UKV0 2/20 0.32
HDAC5 Q9UQL6 2/20 0.32
CYP2D6 P10635 1/20 0.31
TSHR P16473 1/20 0.31
CYP2C19 P33261 1/20 0.31
HIF1A Q16665 1/20 0.31
NOS3 P29474 1/20 0.30
NOS1 P29475 1/20 0.30
NOS2 P35228 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13730363 0.89 ALDH1A1 (0.39) ALDH1A1HDAC3HDAC4HDAC1HDAC7
SCHEMBL988084 0.86 HSD17B10 (0.41) ALDH1A1TDP1HDAC11TSHR
Hydrochloric Acid SCHEMBL1249049 0.84 HSD17B10 (0.40) ALDH1A1TDP1HDAC11TSHR
SCHEMBL1286932 0.84 ALDH1A1 (0.43) ALDH1A1HDAC3HDAC4HDAC1HDAC7
Ethylene SCHEMBL31337284 0.83 HSD17B10 (0.39) ALDH1A1TDP1HDAC11TSHR
SCHEMBL17461346 0.83 CYP1A2 (0.47) ALDH1A1TDP1HDAC3HDAC4HDAC1
SCHEMBL10030117 0.83 TDP1 (0.47) ALDH1A1TDP1HDAC3HDAC4HDAC1
Methoxymethane SCHEMBL30701424 0.82 HSD17B10 (0.38) ALDH1A1TDP1HDAC11TSHR
SCHEMBL17764215 0.80 BLM (0.36) ALDH1A1TDP1HDAC11TSHR
SCHEMBL760267 0.79 ALDH1A1 (0.52) ALDH1A1CYP2D6TSHRCYP2C19HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109734925-B Polymer fluorescence sensor for detecting hypochlorite based on porphyrin comparability, preparation method and application 湖南科技大学 2021-02-02 CN claimed
EP-4719445-A1 PHAGE-EXTRACELLULAR VESICLE CONJUGATE The University Of Sydney (AU) 2026-04-08 EP disclosed
US-20250032636-A1 Phage-Drug Conjugate UNIV SYDNEY (AU) 2025-01-30 US disclosed
WO-2024243637-A1 PHAGE-EXTRACELLULAR VESICLE CONJUGATE THE UNIVERSITY OF SYDNEY (AU) 2024-12-05 WO disclosed
EP-4440589-A1 PHAGE-DRUG CONJUGATE The University Of Sydney (AU) 2024-10-09 EP disclosed
US-11986533-B2 Macromonomers and bottle brush polymers for delivery of biological agents REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2024-05-21 US disclosed
WO-2023092196-A1 PHAGE-DRUG CONJUGATE THE UNIVERSITY OF SYDNEY (AU) 2023-06-01 WO disclosed
US-20220339288-A1 MACROMONOMERS AND BOTTLE BRUSH POLYMERS FOR DELIVERY OF BIOLOGICAL AGENTS REGENTS OF THE UNIVERSITY OF MINNESOTA 2022-10-27 US disclosed
CN-109734925-B Polymer fluorescence sensor for detecting hypochlorite based on porphyrin comparability, preparation method and application 湖南科技大学 2021-02-02 CN disclosed
CN-109734925-B Polymer fluorescence sensor for detecting hypochlorite based on porphyrin comparability, preparation method and application 湖南科技大学 2021-02-02 CN disclosed
US-9914825-B2 Modified heterophasic polyolefin composition MILLIKEN & COMPANY (US) 2018-03-13 US disclosed
US-20160145426-A1 MODIFIED HETEROPHASIC POLYOLEFIN COMPOSITION MILLIKEN & COMPANY 2016-05-26 US disclosed
US-9175015-B2 Gold nanoparticle conjugates and uses thereof COLORADO SCHOOL OF MINES (US) 2015-11-03 US disclosed
US-8337551-B2 Biomedical devices BAUSCH & LOMB INCORPORATED (US) 2012-12-25 US disclosed
US-20120022180-A1 BIOMEDICAL DEVICES BAUSCH & LOMB INCORPORATED 2012-01-26 US disclosed
US-8043369-B2 Biomedical devices BAUSCH & LOMB INCORPORATED (US) 2011-10-25 US disclosed
US-20100317809-A1 Biomedical devices BAUSCH & LOMB INCORPORATED (US) 2010-12-16 US disclosed
US-20090060839-A1 Gold Nanoparticle Conjugates and Uses Thereof COLORADO SCHOOL OF MINES 2009-03-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11986533-B2 Macromonomers and bottle brush polymers for delivery of biological agents HBB, PCNA, ARCN1 ALDH1A1 2240/4885TDP1 2250/4885HDAC3 3098/4885
US-20220339288-A1 MACROMONOMERS AND BOTTLE BRUSH POLYMERS FOR DELIVERY OF BIOLOGICAL AGENTS HBB, PCNA, ARCN1 ALDH1A1 2256/4885TDP1 2251/4885HDAC3 3091/4885
US-20250032636-A1 Phage-Drug Conjugate CLTA, DNPEP, CLTB ALDH1A1 1304/4885TDP1 544/4885HDAC3 3314/4885
US-20090060839-A1 Gold Nanoparticle Conjugates and Uses Thereof CD47, SELP, SELPLG ALDH1A1 419/4885TDP1 1277/4885HDAC3 2939/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.