Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 4/20 | 0.35 |
| ▸ | DRD2 | P14416 | 3/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | CCNK | O75909 | 4/20 | 0.32 |
| ▸ | CDK12 | Q9NYV4 | 4/20 | 0.32 |
| ▸ | HRH2 | P25021 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.32 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.31 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.31 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.31 |
| ▸ | UBE2M | P61081 | 1/20 | 0.30 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1003017 | 1.00 | ADRA1A (0.35) | ADRA1ADRD2CCR5CCNKCDK12 | |
| SCHEMBL1002306 | 0.91 | ADRA1A (0.35) | ADRA1ADRD2CCR5CCNKCDK12 | |
| SCHEMBL1002976 | 0.82 | DRD2 (0.38) | ADRA1ADRD2CCR5ALDH1A1MCHR1 | |
| SCHEMBL1002977 | 0.82 | DRD2 (0.38) | ADRA1ADRD2CCR5ALDH1A1MCHR1 | |
| SCHEMBL12952972 | 0.76 | PIK3CA (0.36) | ADRA1ADRD2CCR5MCHR1 | |
| Hydrochloric Acid SCHEMBL1003146 | 0.75 | DRD2 (0.36) | ADRA1ADRD2ALDH1A1MCHR1SIGMAR1 | |
| SCHEMBL1002520 | 0.73 | DRD2 (0.38) | ADRA1ADRD2CCNKCDK12MCHR1 | |
| SCHEMBL1005478 | 0.73 | DRD2 (0.38) | ADRA1ADRD2CCNKCDK12MCHR1 | |
| SCHEMBL2877440 | 0.72 | MCHR1 (0.45) | ADRA1ADRD2CCNKCDK12HRH2 | |
| SCHEMBL2877441 | 0.72 | MCHR1 (0.45) | ADRA1ADRD2CCNKCDK12HRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110015198-A1 | DIARYLMETHYLAMIDE DERIVATIVE HAVING MELANIN-CONCENTRATING HORMONE RECEPTOR ANTAGONISM | BANYU PHARMACEUTICAL CO., INC. | 2011-01-20 | — | — | US | disclosed |
| EP-2272841-A1 | DIARYLMETHYLAMIDE DERIVATIVE HAVING ANTAGONISTIC ACTIVITY ON MELANIN-CONCENTRATING HORMONE RECEPTOR | Banyu Pharmaceutical Co., Ltd. (JP) | 2011-01-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110015198-A1 | DIARYLMETHYLAMIDE DERIVATIVE HAVING MELANIN-CONCENTRATING HORMONE RECEPTOR ANTAGONISM | MC1R, MCHR2, MCHR1 | ADRA1A 38/4885DRD2 164/4885CCR5 2726/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.