Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 5/20 | 0.36 |
| ▸ | PRKAA2 | P54646 | 5/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 3/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 3/20 | 0.32 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.32 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.32 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.32 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.32 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.32 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | CTSC | P53634 | 2/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1002977 | 0.93 | DRD2 (0.38) | PIK3CAPRKAA2PARP1DRD2ADRA1A | |
| SCHEMBL1002976 | 0.93 | DRD2 (0.38) | PIK3CAPRKAA2PARP1DRD2ADRA1A | |
| SCHEMBL1001395 | 0.81 | DRD2 (0.38) | PIK3CAPRKAA2PARP1DRD2ADRA1A | |
| SCHEMBL1001396 | 0.81 | DRD2 (0.38) | PIK3CAPRKAA2PARP1DRD2ADRA1A | |
| SCHEMBL1003096 | 0.77 | DRD2 (0.39) | PARP1DRD2ADRA1AKCNH2CCR5 | |
| SCHEMBL1003094 | 0.77 | DRD2 (0.39) | PARP1DRD2ADRA1AKCNH2CCR5 | |
| SCHEMBL1003017 | 0.76 | ADRA1A (0.35) | DRD2ADRA1ACCR5MCHR1 | |
| SCHEMBL1003018 | 0.76 | ADRA1A (0.35) | DRD2ADRA1ACCR5MCHR1 | |
| SCHEMBL1003710 | 0.72 | DRD2 (0.42) | DRD2ADRA1AKCNH2CCR5MCHR1 | |
| SCHEMBL1003708 | 0.72 | DRD2 (0.42) | DRD2ADRA1AKCNH2CCR5MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2272841-A1 | DIARYLMETHYLAMIDE DERIVATIVE HAVING ANTAGONISTIC ACTIVITY ON MELANIN-CONCENTRATING HORMONE RECEPTOR | Banyu Pharmaceutical Co., Ltd. (JP) | 2011-01-12 | — | — | EP | disclosed |