Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.69 |
| ▸ | RAB9A | P51151 | 3/20 | 0.69 |
| ▸ | MAPT | P10636 | 2/20 | 0.69 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 13/20 | 0.41 |
| ▸ | MAOB | P27338 | 8/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3630819 | 0.89 | NPC1 (0.50) | NPC1RAB9AMAPTPOLBCYP2C9 | |
| SCHEMBL128091 | 0.87 | NPC1 (0.81) | NPC1RAB9AMAPTPOLBCYP2C9 | |
| SCHEMBL21671652 | 0.84 | NPC1 (0.49) | NPC1RAB9AMAPTPOLBCYP2C9 | |
| SCHEMBL18330670 | 0.82 | HRH3 (0.49) | NPC1RAB9AMAPTALDH1A1HRH3 | |
| SCHEMBL11050500 | 0.82 | RXRA (0.55) | NPC1RAB9AMAPTPOLBALDH1A1 | |
| SCHEMBL15054796 | 0.81 | MAPT (1.00) | NPC1RAB9AMAPTPOLBCYP2C9 | |
| SCHEMBL172604 | 0.81 | RAB9A (0.64) | NPC1RAB9AMAPTPOLBCYP2C9 | |
| SCHEMBL10000943 | 0.81 | MAPT (0.48) | NPC1RAB9AMAPTCYP2C9ALDH1A1 | |
| SCHEMBL9923543 | 0.79 | NPC1 (0.70) | NPC1RAB9AMAPTPOLBCYP2C9 | |
| SCHEMBL2607726 | 0.79 | NPC1 (0.70) | NPC1RAB9AMAPTPOLBCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120160317-A1 | POLYIMIDE POLYMER SOLUTION, POLYIMIDE POLYMER, TRANSPARENT FILM, DISPLAYING DEVICE AND SOLAR CELL | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2012-06-28 | — | — | US | disclosed |