SCHEMBL172604

SCHEMBL172604

CC(C)c1ccc(Oc2ccc(C(C)(C)C)cc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 4/20 0.64
NPC1 O15118 3/20 0.64
ALDH1A1 P00352 3/20 0.64
HPGD P15428 3/20 0.64
MAPT P10636 2/20 0.64
MAPK1 P28482 1/20 0.64
KDM4E B2RXH2 2/20 0.42
POLB P06746 1/20 0.42
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
HIF1A Q16665 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA9 Q16790 1/20 0.41
TSHR P16473 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
MEN1 O00255 1/20 0.39
HTT P42858 1/20 0.39
BLM P54132 1/20 0.39
KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26818921 0.94 RAB9A (0.58) RAB9ANPC1ALDH1A1HPGDMAPT
SCHEMBL10000939 0.94 RAB9A (0.58) RAB9ANPC1ALDH1A1HPGDMAPT
SCHEMBL24863566 0.89 RAB9A (0.53) RAB9ANPC1ALDH1A1HPGDMAPT
SCHEMBL10000948 0.88 ALDH1A1 (0.51) RAB9ANPC1ALDH1A1HPGDMAPT
SCHEMBL10000943 0.88 MAPT (0.48) RAB9ANPC1ALDH1A1HPGDMAPT
SCHEMBL548066 0.87 TSHR (0.50) RAB9ANPC1ALDH1A1HPGDMAPT
SCHEMBL19351066 0.87 SRD5A2 (0.53) RAB9ANPC1ALDH1A1HPGDMAPT
SCHEMBL22275948 0.87 NPC1 (0.50) RAB9ANPC1ALDH1A1HPGDMAPT
SCHEMBL10000938 0.87 ALDH1A1 (0.50) RAB9ANPC1ALDH1A1HPGDMAPT
SCHEMBL10975203 0.86 MAPT (0.51) RAB9ANPC1ALDH1A1HPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3996899-B1 POWDER BED FUSION MATERIAL AND METHOD SHPP GLOBAL TECH BV (NL) 2023-08-30 EP disclosed
US-11374175-B2 Polymer, coating composition comprising same, and organic light-emitting device using same LG CHEM, LTD. 2022-06-28 US disclosed
US-11027242-B2 Nanofiltration membranes and methods of use NOVOMER, INC. (US) 2021-06-08 US disclosed
US-10844179-B2 Bridged silicone resin, film, electronic device and related methods DOW SILICONES CORPORATION (US) 2020-11-24 US disclosed
US-20200172678-A1 BRIDGED SILICONE RESIN, FILM, ELECTRONIC DEVICE AND RELATED METHODS DOW SILICONES CORPORATION 2020-06-04 US disclosed
US-20190255488-A1 NANOFILTRATION MEMBRANES AND METHODS OF USE NOVOMER, INC. (US) 2019-08-22 US disclosed
US-20190185624-A1 BIOCOMPATIBLE POLYMERS FOR MEDICAL DEVICES RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY 2019-06-20 US disclosed
US-10312502-B2 Lithium electrode and lithium secondary battery comprising same LG CHEM, LTD. (KR) 2019-06-04 US disclosed
US-10245559-B2 Nanofiltration membranes and methods of use NOVOMER, INC. (US) 2019-04-02 US disclosed
US-9876211-B2 Separation membrane and lithium-sulfur battery comprising same LG CHEM, LTD. (KR) 2018-01-23 US disclosed
US-20170226054-A1 FLUORINE-BASED COMPOUND FOR BRANCHER, POLYMER USING SAME, AND POLYMER ELECTROLYTE MEMBRANE USING SAME LG CHEM, LTD. (KR) 2017-08-10 US disclosed
US-20170104209-A1 LITHIUM ELECTRODE AND LITHIUM SECONDARY BATTERY COMPRISING SAME LG CHEM, LTD. (KR) 2017-04-13 US disclosed
US-8859715-B2 Polyimide polymer solution, polyimide polymer, transparent film, displaying device and solar cell INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2014-10-14 US disclosed
US-20120160317-A1 POLYIMIDE POLYMER SOLUTION, POLYIMIDE POLYMER, TRANSPARENT FILM, DISPLAYING DEVICE AND SOLAR CELL INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2012-06-28 US disclosed
EP-1255738-B1 GONADOTROPIN-RELEASING HORMONE RECEPTOR ANTAGONISTS AND METHODS RELATING THERETO NEUROCRINE BIOSCIENCES INC (US) 2012-03-07 EP disclosed
US-7462625-B2 Gonadotropin-releasing hormone receptor antagonists and methods relating thereto NEUROCRINE BIOSCIENCES, INC. (US) 2008-12-09 US disclosed
US-7462625-B2 Gonadotropin-releasing hormone receptor antagonists and methods relating thereto NEUROCRINE BIOSCIENCES, INC. (US) 2008-12-09 US disclosed
US-20070208049-A1 Gonadotropin-releasing hormone receptor antagonists and methods relating thereto NEUROCRINE BIOSCIENCES, INC. (US) 2007-09-06 US disclosed
US-20070208049-A1 Gonadotropin-releasing hormone receptor antagonists and methods relating thereto NEUROCRINE BIOSCIENCES, INC. (US) 2007-09-06 US disclosed
US-7179815-B2 Gonadotropin-releasing hormone receptor antagonists and methods relating thereto NEUROCRINE BIOSCIENCES, INC. (US) 2007-02-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10245559-B2 Nanofiltration membranes and methods of use MLEC, EPCAM, LNPK RAB9A 1123/4885NPC1 698/4885ALDH1A1 1130/4885
US-20190255488-A1 NANOFILTRATION MEMBRANES AND METHODS OF USE MLEC, EPCAM, LNPK RAB9A 1123/4885NPC1 698/4885ALDH1A1 1130/4885
US-11027242-B2 Nanofiltration membranes and methods of use MLEC, EPCAM, LNPK RAB9A 1123/4885NPC1 698/4885ALDH1A1 1130/4885
US-20170226054-A1 FLUORINE-BASED COMPOUND FOR BRANCHER, POLYMER USING SAME, AND POLYMER ELECTROLYTE MEMBRANE USING SAME AFF4, AFF2, PFAS RAB9A 2524/4885NPC1 1852/4885ALDH1A1 985/4885
US-20070208049-A1 Gonadotropin-releasing hormone receptor antagonists and methods relating thereto GNRHR, GHRHR, LHCGR RAB9A 1093/4885NPC1 1959/4885ALDH1A1 3443/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.