SCHEMBL10030480

SCHEMBL10030480

C=C(C)C(=O)OCCNc1nc(Nc2ccccc2)nc(Nc2ccccc2)n1

nearest known ligand 0.60

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KCNH3 Q9ULD8 12/20 0.60
RECQL P46063 1/20 0.54
MCL1 Q07820 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22356476 0.88 KCNH3 (0.48) KCNH3RECQLMCL1
SCHEMBL22356379 0.88 KCNH3 (0.48) KCNH3RECQLMCL1
SCHEMBL7640048 0.84 MAPT (0.45) KCNH3
SCHEMBL305728 0.83 POLB (0.44) RECQL
SCHEMBL22356357 0.82 HTT (0.50) KCNH3
SCHEMBL22356362 0.82 HTT (0.50) KCNH3
Hydrochloric Acid SCHEMBL11047494 0.82 POLB (0.43) KCNH3RECQL
SCHEMBL10030481 0.80 PAX8 (0.48) KCNH3RECQL
SCHEMBL22356361 0.80 RHOA (0.46)
SCHEMBL22356356 0.80 RHOA (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9012582-B2 Transparent high-refractive-index resin composition NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2015-04-21 US disclosed
US-9012582-B2 Transparent high-refractive-index resin composition NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2015-04-21 US disclosed
US-20120142878-A1 TRANSPARENT HIGH-REFRACTIVE-INDEX RESIN COMPOSITION NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2012-06-07 US disclosed
US-20120142878-A1 TRANSPARENT HIGH-REFRACTIVE-INDEX RESIN COMPOSITION NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2012-06-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120142878-A1 TRANSPARENT HIGH-REFRACTIVE-INDEX RESIN COMPOSITION TERB1, H1-5, RRP15 KCNH3 2317/4885RECQL 536/4885MCL1 4650/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.