Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CA9 | Q16790 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10030483 | 0.82 | PAX8 (0.52) | PAX8MAPK1HTTPOLBAPEX1 | |
| SCHEMBL10030480 | 0.80 | KCNH3 (0.60) | RECQLKCNH3 | |
| SCHEMBL28667907 | 0.76 | ALDH1A1 (0.47) | HTTPOLBAPEX1TDP1MEN1 | |
| SCHEMBL305728 | 0.76 | POLB (0.44) | HTTPOLBAPEX1TDP1SMN1; SMN2 | |
| SCHEMBL10030486 | 0.76 | PAX8 (0.45) | PAX8MAPK1HTTPOLBAPEX1 | |
| SCHEMBL22356476 | 0.75 | KCNH3 (0.48) | HTTKDM4ERECQLKCNH3 | |
| SCHEMBL22356379 | 0.75 | KCNH3 (0.48) | HTTKDM4ERECQLKCNH3 | |
| Hydrochloric Acid SCHEMBL11047494 | 0.74 | POLB (0.43) | HTTPOLBAPEX1TDP1SMN1; SMN2 | |
| SCHEMBL9683157 | 0.73 | THRB (0.40) | CA1CA2CA9MAPK1HTT | |
| SCHEMBL11189569 | 0.73 | MAPK1 (0.52) | CA1CA2CA9MAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9012582-B2 | Transparent high-refractive-index resin composition | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2015-04-21 | — | — | US | disclosed |
| US-9012582-B2 | Transparent high-refractive-index resin composition | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2015-04-21 | — | — | US | disclosed |
| US-20120142878-A1 | TRANSPARENT HIGH-REFRACTIVE-INDEX RESIN COMPOSITION | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2012-06-07 | — | — | US | disclosed |
| US-20120142878-A1 | TRANSPARENT HIGH-REFRACTIVE-INDEX RESIN COMPOSITION | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142878-A1 | TRANSPARENT HIGH-REFRACTIVE-INDEX RESIN COMPOSITION | TERB1, H1-5, RRP15 | PAX8 3367/4885CA1 3137/4885CA2 3733/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.