Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 9/20 | 0.74 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.71 |
| ▸ | CCR1 | P32246 | 7/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10064332 | 0.88 | KCNA3 (0.78) | KCNA3OPRM1CCR1RAB9ANPSR1 | |
| Difenoxin SCHEMBL123801 | 0.88 | KCNA3 (0.78) | KCNA3OPRM1CCR1RAB9ANPSR1 | |
| Difenoxin SCHEMBL11604884 | 0.86 | KCNA3 (0.76) | KCNA3OPRM1CCR1RAB9ANPSR1 | |
| Difenoxin SCHEMBL149008 | 0.86 | KCNA3 (0.76) | KCNA3OPRM1CCR1RAB9ANPSR1 | |
| SCHEMBL10065583 | 0.86 | KCNA3 (0.76) | KCNA3OPRM1CCR1RAB9ANPSR1 | |
| SCHEMBL11604250 | 0.84 | KCNA3 (0.84) | KCNA3OPRM1CCR1RAB9ANPSR1 | |
| Hydrochloric Acid SCHEMBL11604880 | 0.84 | KCNA3 (0.73) | KCNA3OPRM1CCR1RAB9ANPSR1 | |
| Diphenoxylate SCHEMBL42940 | 0.83 | OPRM1 (1.00) | KCNA3OPRM1 | |
| Diphenoxylate SCHEMBL20595320 | 0.82 | OPRM1 (0.98) | KCNA3OPRM1 | |
| Diphenoxylate SCHEMBL42124 | 0.82 | OPRM1 (0.98) | KCNA3OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120046272-A1 | Novel Therapeutic Compounds | GRUNENTHAL GMBH (DE) | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046272-A1 | Novel Therapeutic Compounds | OPRL1, OPRK1, OPRM1 | KCNA3 1326/4885OPRM1 3/4885CCR1 336/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.