Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.36 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38662397 | 1.00 | CHRM1 (0.46) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL1003227 | 1.00 | CHRM1 (0.46) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL8488815 | 0.87 | CA2 (0.47) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL1474367 | 0.87 | CA2 (0.47) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL2963668 | 0.87 | CA2 (0.47) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL2962104 | 0.85 | GPR84 (0.48) | GRIK1SLC1A2SLC1A1GRIK2CA2 | |
| SCHEMBL868772 | 0.85 | GPR84 (0.48) | GRIK1SLC1A2SLC1A1GRIK2CA2 | |
| SCHEMBL5331357 | 0.84 | GPR84 (0.52) | GRIK1SLC1A2SLC1A1GRIK2GPR84 | |
| SCHEMBL5047820 | 0.84 | GPR84 (0.52) | GRIK1SLC1A2SLC1A1GRIK2GPR84 | |
| SCHEMBL5331360 | 0.84 | GPR84 (0.52) | GRIK1SLC1A2SLC1A1GRIK2GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117129590-A | Application of endogenous metabolite in preparation of aplastic anemia diagnosis product | 苏州派博思生物技术有限公司 | 2023-11-28 | — | — | CN | claimed |
| CN-117129590-A | Application of endogenous metabolite in preparation of aplastic anemia diagnosis product | 苏州派博思生物技术有限公司 | 2023-11-28 | — | — | CN | disclosed |
| CN-115812710-A | Insect repellent composition comprising one or more insect repellent fatty acids having 9 to 21 carbon atoms | 长荣置地有限公司 | 2023-03-21 | — | — | CN | disclosed |
| CN-112118739-B | Insect repellent composition comprising one or more insect repellent fatty acids having 9 to 21 carbon atoms | 长荣置地有限公司 | 2023-01-10 | — | — | CN | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| CN-112118739-A | Insect repellent composition comprising one or more insect repellent fatty acids having 9 to 21 carbon atoms | 长荣置地有限公司 | 2020-12-22 | — | — | CN | disclosed |
| US-20190391092-A1 | METABOLIC PROFILING WITH MAGNETIC RESONANCE MASS SPECTROMETRY (MRMS) | Oregon Institute of Science and Medicine | 2019-12-26 | — | — | US | disclosed |
| US-8367792-B2 | Polysiloxane compound and method of producing the same | JNC CORPORATION (JP) | 2013-02-05 | — | — | US | disclosed |
| US-20120208973-A1 | POLYSILOXANE COMPOUND AND METHOD OF PRODUCING THE SAME | OOTAKE NOBUMASA (JP) | 2012-08-16 | — | — | US | disclosed |
| EP-2456433-A2 | METHODS FOR THE PREPARATION AND USE OF AQUEOUS SOLUTIONS OF MAGNESIUM VALPROATE HYDRATE AND L-CARNITINE | Biolink Life Sciences, Inc. (US) | 2012-05-30 | — | — | EP | disclosed |
| EP-0659172-A1 | ANALOGUES OF VPA USED AS ANTI-EPILEPTICA. | NAU HEINZ (DE) | 1995-06-28 | — | — | EP | disclosed |
| EP-0632008-A1 | Pentanoic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-01-04 | — | — | EP | disclosed |
| WO-1994006743-A1 | ANALOGUES OF VPA USED AS ANTI-EPILEPTICA | NAU HEINZ (DE) | 1994-03-31 | — | — | WO | disclosed |
| US-4966996-A | Process for the preparation of E-2-propyl-2-pentenoic acid and physiologically compatible salts thereof | Desitin Arznemittel GmbH (DE) | 1990-10-30 | — | — | US | disclosed |
| EP-0293753-A2 | Process for preparing E-2-propyl-2-pentenoic acid and its physiologically compatible salts | Desitin Arzneimittel GmbH (DE) | 1988-12-07 | — | — | EP | disclosed |
| EP-0043285-B2 | METHOD FOR DETERMINATION OF VALPROIC ACID AND REAGENTS THEREIN | Dainippon Pharmaceutical Co., Ltd. (JP) | 1988-06-22 | — | — | EP | disclosed |
| US-4443365-A | Method for determination of the valproic acid and reagents therein | DAINIPPON PHARMACEUTICAL COMPANY LIMITED (JP) | 1984-04-17 | — | — | US | disclosed |
| US-4432985-A | N-alkylated carboxylic acid derivatives as anti-convulsant agents | ABBOTT LABORATORIES (US) | 1984-02-21 | — | — | US | disclosed |
| EP-0043285-B1 | METHOD FOR DETERMINATION OF VALPROIC ACID AND REAGENTS THEREIN | Dainippon Pharmaceutical Co., Ltd. (JP) | 1984-01-04 | — | — | EP | disclosed |
| EP-0043285-A1 | Method for determination of valproic acid and reagents therein | Dainippon Pharmaceutical Co., Ltd. (JP) | 1982-01-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120208973-A1 | POLYSILOXANE COMPOUND AND METHOD OF PRODUCING THE SAME | RPS4X, POLR2A, MSL1 | CHRM1 463/4885AKR1A1 2078/4885CHRM3 1281/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.