Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 9/20 | 0.51 |
| ▸ | CYP11B1 | P15538 | 8/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.51 |
| ▸ | CYP17A1 | P05093 | 4/20 | 0.51 |
| ▸ | GSK3B | P49841 | 2/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.38 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10032855 | 0.96 | CYP11B2 (0.52) | CYP11B2CYP11B1CYP19A1CYP17A1GSK3B | |
| SCHEMBL10032641 | 0.85 | ABL1 (0.40) | CYP11B2CYP11B1CYP19A1CYP17A1GSK3B | |
| SCHEMBL17320827 | 0.84 | CYP11B2 (0.57) | CYP11B2CYP11B1CYP19A1CYP17A1PGR | |
| SCHEMBL13015741 | 0.84 | CYP11B2 (0.68) | CYP11B2CYP11B1CYP19A1CYP17A1CYP2A6 | |
| SCHEMBL10032352 | 0.83 | CYP11B2 (0.56) | CYP11B2CYP11B1CYP19A1CYP17A1GSK3B | |
| SCHEMBL10032629 | 0.83 | CYP11B2 (0.39) | CYP11B2CYP11B1CYP19A1CYP17A1GSK3B | |
| SCHEMBL13016102 | 0.82 | CYP11B2 (0.67) | CYP11B2CYP11B1CYP19A1CYP17A1PGR | |
| SCHEMBL10032724 | 0.80 | KIF11 (0.56) | CYP11B2CYP11B1CYP19A1CYP17A1PGR | |
| SCHEMBL9887608 | 0.80 | CYP11B2 (0.76) | CYP11B2CYP11B1CYP19A1CYP17A1PGR | |
| SCHEMBL10032669 | 0.80 | CYP11B2 (0.51) | CYP11B2CYP11B1CYP19A1CYP17A1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012060374-A1 | ELECTRON TRANSPORT MATERIAL AND ORGANIC ELECTROLUMINESCENCE ELEMENT USING SAME | JNC株式会社 (JP) | 2012-05-10 | — | — | WO | disclosed |