SCHEMBL10032629

SCHEMBL10032629

c1cc(-c2c3ccccc3c(-c3ccc4ccc(-c5cncc(-c6ccncc6)c5)cc4c3)c3ccccc23)cc(C2CC2)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B2 P19099 4/20 0.39
CYP11B1 P15538 3/20 0.39
CYP17A1 P05093 2/20 0.38
CYP19A1 P11511 1/20 0.38
HSD17B1 P14061 1/20 0.36
HSD17B2 P37059 1/20 0.36
DHODH Q02127 1/20 0.36
PRMT5 O14744 1/20 0.35
WDR77 Q9BQA1 1/20 0.35
DYRK1A Q13627 5/20 0.35
PDGFRB P09619 1/20 0.35
PDGFRA P16234 1/20 0.35
ABL1 P00519 1/20 0.34
KCNH2 Q12809 1/20 0.34
MAP3K5 Q99683 1/20 0.33
ROCK2 O75116 1/20 0.33
CHRNB1 P11230 1/20 0.33
CHRNB2 P17787 1/20 0.33
CHRNB4 P30926 1/20 0.33
CHRNA3 P32297 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10032628 0.83 CYP11B2 (0.51) CYP11B2CYP11B1CYP17A1CYP19A1HSD17B1
SCHEMBL10032169 0.81 MAPK14 (0.47) CYP11B2CYP11B1CYP17A1CYP19A1HSD17B1
SCHEMBL17320815 0.81 PRKCZ (0.49) CYP11B2CYP11B1CYP17A1CYP19A1HSD17B1
SCHEMBL17320827 0.81 CYP11B2 (0.57) CYP11B2CYP11B1CYP17A1CYP19A1HSD17B1
SCHEMBL13015319 0.80 CYP11B1 (0.55) CYP11B2CYP11B1CYP17A1CYP19A1HSD17B1
SCHEMBL10032855 0.79 CYP11B2 (0.52) CYP11B2CYP11B1CYP17A1CYP19A1HSD17B1
SCHEMBL13015329 0.79 CYP11B1 (0.49) CYP11B2CYP11B1CYP17A1CYP19A1PDGFRB
SCHEMBL13015645 0.79 CYP17A1 (0.51) CYP11B2CYP11B1CYP17A1CYP19A1HSD17B1
SCHEMBL10032641 0.78 ABL1 (0.40) CYP11B2CYP11B1CYP17A1CYP19A1DHODH
SCHEMBL10032595 0.76 CYP11B2 (0.44) CYP11B2CYP11B1CYP17A1CYP19A1DHODH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012060374-A1 ELECTRON TRANSPORT MATERIAL AND ORGANIC ELECTROLUMINESCENCE ELEMENT USING SAME JNC株式会社 (JP) 2012-05-10 WO disclosed