SCHEMBL1003276

SCHEMBL1003276

CCCC(Cl)CC(C)(C)O[SiH3]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17669095 0.88
SCHEMBL17669041 0.86 OPRM1 (0.31)
SCHEMBL558282 0.82
SCHEMBL28891698 0.74
SCHEMBL29795209 0.74 TSHR (0.30)
SCHEMBL28805394 0.72
SCHEMBL613324 0.72
SCHEMBL703921 0.70 ALDH1A1 (0.37)
SCHEMBL17669036 0.68
SCHEMBL28418318 0.67 MMP13 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7863398-B2 Process for making hydrolyzable silylated polymers MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2011-01-04 US claimed
EP-2134767-B1 PROCESS FOR MAKING HYDROLYZABLE SILYLATED POLYMERS MOMENTIVE PERFORMANCE MAT INC (US) 2010-09-15 EP claimed
EP-2134767-A1 PROCESS FOR MAKING HYDROLYZABLE SILYLATED POLYMERS Momentive Performance Materials Inc. (US) 2009-12-23 EP claimed
US-20080242825-A1 Process for making hydrolyzable silylated polymers MOMENTIVE PERFORMANCE MATERIALS INC. 2008-10-02 US claimed
WO-2008118460-A1 PROCESS FOR MAKING HYDROLYZABLE SILYLATED POLYMERS MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2008-10-02 WO claimed
EP-3009439-B1 CYCLIC AMINOORGANOXYSILANE COMPOUND AND ITS PRODUCTION METHOD SHINETSU CHEMICAL CO (JP) 2018-01-03 EP disclosed
US-9371341-B2 Cyclic aminoorganoxysilane compound and its production method SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-06-21 US disclosed
EP-3009439-A1 CYCLIC AMINOORGANOXYSILANE COMPOUND AND ITS PRODUCTION METHOD Shin-Etsu Chemical Co., Ltd. (JP) 2016-04-20 EP disclosed
US-20160102111-A1 CYCLIC AMINOORGANOXYSILANE COMPOUND AND ITS PRODUCTION METHOD SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-04-14 US disclosed
US-5905150-A HEATING IN PRESENCE OF PHASE TRANSFER AGENT GENERAL ELECTRIC COMPANY (US) 1999-05-18 US disclosed
EP-0900801-A1 Process for preparing organosilanes GENERAL ELECTRIC COMPANY (US) 1999-03-10 EP disclosed